Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13369309 | 0.79 | ALDH1A1 (0.52) | ALDH1A1FTOPLA2G7 | |
| SCHEMBL7535989 | 0.74 | FTO (0.45) | ALDH1A1FTO | |
| SCHEMBL13369212 | 0.73 | ALDH1A1 (0.42) | ALDH1A1FTO | |
| SCHEMBL5141219 | 0.71 | ALDH1A1 (0.40) | ALDH1A1FTO | |
| SCHEMBL15658000 | 0.70 | FTO (0.42) | ALDH1A1FTOHTR7 | |
| SCHEMBL7192578 | 0.70 | FTO (0.42) | ALDH1A1FTOHTR7 | |
| SCHEMBL15657999 | 0.70 | FTO (0.42) | ALDH1A1FTOHTR7 | |
| SCHEMBL16533076 | 0.68 | ALDH1A1 (0.47) | ALDH1A1FTOPLA2G7 | |
| SCHEMBL2653141 | 0.67 | ALDH1A1 (0.61) | ALDH1A1PLA2G7HTR7 | |
| SCHEMBL27708379 | 0.67 | TBXAS1 (0.54) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007955-A2 | BIPHENYL APURINIC/APYRIMIDINIC SITE ENDONUCLEASE INHIBITORS TO TREAT CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-01-30 | — | — | WO | disclosed |