Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192591 | 0.79 | GAA (0.57) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL9502514 | 0.75 | ELANE (0.49) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL3988877 | 0.73 | GAA (0.57) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL28351931 | 0.72 | ELANE (0.46) | KDM4EALDH1A1GAAHSD17B10GABRA1 | |
| SCHEMBL28194247 | 0.70 | MAOA (0.53) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL167075 | 0.69 | GABRA1 (0.54) | KDM4EALDH1A1GAAHSD17B10GABRA1 | |
| SCHEMBL7201805 | 0.68 | IGF1R (0.42) | KDM4EALDH1A1HSD17B10GABRA1GABRB2 | |
| SCHEMBL18136 | 0.67 | GABRA1 (0.56) | KDM4EALDH1A1GAAHSD17B10GABRA1 | |
| SCHEMBL1570705 | 0.67 | GABRA1 (0.47) | KDM4EALDH1A1GAAHSD17B10GABRA1 | |
| SCHEMBL3267547 | 0.66 | MAOA (0.54) | KDM4EALDH1A1HPGDCYP1A2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023597-A1 | Single Nucleotide Polymorphism Detection from Unamplified Genomic DNA | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2009-01-22 | — | — | US | disclosed |
| EP-2002020-A2 | SINGLE NUCLEOTIDE POLYMORPHISM DETECTION FROM UNAMPLIFIED GENOMIC DNA | Siemens Healthcare Diagnostics Inc. (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007120843-A2 | SINGLE NUCLEOTIDE POLYMORPHISM DETECTION FROM UNAMPLIFIED GENOMIC DNA | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2007-10-25 | — | — | WO | disclosed |