Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20015760 | 0.86 | CYP2A6 (0.57) | LMNACYP2A6APPMAOAMAOB | |
| SCHEMBL1246271 | 0.86 | CYP2A6 (0.57) | LMNACYP2A6APPMAOAMAOB | |
| SCHEMBL20015814 | 0.86 | LMNA (0.57) | KCNH2GRM5LMNACYP2A6APP | |
| SCHEMBL719360 | 0.86 | LMNA (0.57) | KCNH2GRM5LMNACYP2A6APP | |
| Charcoal, Activated SCHEMBL31286310 | 0.83 | KCNH2 (0.54) | KCNH2GRM5LMNACYP2A6APP | |
| SCHEMBL197605 | 0.83 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL10839178 | 0.83 | CYP2A6 (0.61) | LMNACYP2A6DRD4MEN1KMT2A | |
| Water SCHEMBL15842032 | 0.80 | — | — | |
| Fluoride SCHEMBL2941684 | 0.80 | CYP2A6 (0.57) | LMNACYP2A6DRD4MEN1KMT2A | |
| Magnesium SCHEMBL30533117 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538623-B1 | COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP | MERCK PATENT GMBH (DE) | 2023-12-20 | — | — | EP | disclosed |
| US-20230354701-A1 | COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP | MERCK PATENT GMBH (DE) | 2023-11-02 | — | — | US | disclosed |
| EP-4271163-A2 | COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP | Merck Patent GmbH (DE) | 2023-11-01 | — | — | EP | disclosed |
| US-11711976-B2 | Compounds with an acceptor and a donor group | MERCK PATENT GMBH (DE) | 2023-07-25 | — | — | US | disclosed |
| US-20200203624-A1 | COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | US | disclosed |
| EP-3538623-A1 | COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP | Merck Patent GmbH (DE) | 2019-09-18 | — | — | EP | disclosed |
| US-7479575-B2 | Method for preparing para-phenyl alkynyl benzaldehydes | LABORATOIRES SERONO SA (CH) | 2009-01-20 | — | — | US | disclosed |
| US-7479575-B2 | Method for preparing para-phenyl alkynyl benzaldehydes | LABORATOIRES SERONO SA (CH) | 2009-01-20 | — | — | US | disclosed |
| US-20080108849-A1 | Method For Preparing Para-Phenyl Alkynyl Benzaldehydes | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2008-05-08 | — | — | US | disclosed |
| US-20080108849-A1 | Method For Preparing Para-Phenyl Alkynyl Benzaldehydes | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2008-05-08 | — | — | US | disclosed |
| EP-1675813-B1 | METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES | SERONO LAB (CH) | 2007-12-19 | — | — | EP | disclosed |
| EP-1675813-B1 | METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES | SERONO LAB (CH) | 2007-12-19 | — | — | EP | disclosed |
| EP-1675813-A1 | METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES | Applied Research Systems ARS Holding N.V. (NL) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005037758-A1 | METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108849-A1 | Method For Preparing Para-Phenyl Alkynyl Benzaldehydes | TNNC1, CPT1B, MUSK | KCNH2 7/4885GRM5 3609/4885LMNA 18/4885 |
| US-11711976-B2 | Compounds with an acceptor and a donor group | NQO1, ICMT, NUDT1 | KCNH2 286/4885GRM5 2589/4885LMNA 4314/4885 |
| US-20200203624-A1 | COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP | NQO1, ICMT, NUDT1 | KCNH2 286/4885GRM5 2589/4885LMNA 4314/4885 |
| US-20230354701-A1 | COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP | NQO1, ICMT, NUDT1 | KCNH2 286/4885GRM5 2589/4885LMNA 4314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.