Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CCL2 | P13500 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL647140 | 0.96 | HTR2A (0.36) | HTR2AHTR6SIGMAR1BRD4CCL2 | |
| Hydrochloric Acid SCHEMBL218233 | 0.96 | HTR2A (0.36) | HTR2AHTR6SIGMAR1BRD4CCL2 | |
| Toluene SCHEMBL7811133 | 0.87 | LMNA (0.38) | HTR2AHTR6SIGMAR1LMNA | |
| Phenol SCHEMBL23921982 | 0.87 | HTR6 (0.35) | HTR2AHTR6SIGMAR1 | |
| SCHEMBL7934756 | 0.84 | BRD4 (0.34) | HTR2AHTR6SIGMAR1BRD4CCL2 | |
| Hydrochloric Acid SCHEMBL7716227 | 0.82 | HTR6 (0.31) | HTR2AHTR6CYP2D6 | |
| Trifluoromethanesulfonic Acid SCHEMBL6533219 | 0.81 | GPR3 (0.37) | — | |
| Hydrochloric Acid SCHEMBL30533389 | 0.78 | HTR2A (0.39) | HTR2AHTR6SIGMAR1BRD4CCL2 | |
| SCHEMBL7155577 | 0.78 | FFAR4 (0.35) | KDM4ELMNACYP3A4CYP2D6THPO | |
| Hydrochloric Acid SCHEMBL442912 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974601-B1 | Olefin polymerization catalyst and process for producing olefin polymer | JAPAN POLYCHEM CORP (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6376416-B1 | COORDINATION POLYMERIZATION CATALYSTS | JAPAN POLYCHEM CORPORATION (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-0974601-A2 | Olefin polymerization catalyst and process for producing olefin polymer | Japan Polychem Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |