SCHEMBL7934756

SCHEMBL7934756

C=[Zr+2](C1C=Cc2ccccc21)C1C=Cc2ccccc21.CS(=O)(=O)[O-].CS(=O)(=O)[O-]

nearest known ligand 0.34

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR2A known ✓ P28223 1/20 0.30
BRD4 O60885 1/20 0.34
CCL2 P13500 1/20 0.34
SIGMAR1 Q99720 2/20 0.31
HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7155577 0.87 FFAR4 (0.35)
Trifluoromethanesulfonic Acid SCHEMBL6533219 0.86 GPR3 (0.37)
SCHEMBL7155580 0.84 ALDH1A1 (0.34)
SCHEMBL7195752 0.84 HTR2A (0.36) BRD4CCL2SIGMAR1HTR6HTR2A
Hydrochloric Acid SCHEMBL647140 0.84 HTR2A (0.36) BRD4CCL2SIGMAR1HTR6HTR2A
Hydrochloric Acid SCHEMBL218233 0.84 HTR2A (0.36) BRD4CCL2SIGMAR1HTR6HTR2A
Phenol SCHEMBL23921982 0.80 HTR6 (0.35) SIGMAR1HTR6HTR2A
Toluene SCHEMBL7811133 0.80 LMNA (0.38) SIGMAR1HTR6HTR2A
Hydrochloric Acid SCHEMBL7716227 0.72 HTR6 (0.31) HTR6HTR2A
Trifluoromethanesulfonic Acid SCHEMBL7199726 0.71 GPR3 (0.35) BRD4CCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6329465-B1 TRANSPARENCY, MECHANICAL STRENGTH AND MOLDABILITY MITSUI CHEMICAL INC (JP) 2001-12-11 US disclosed
EP-1086963-A1 USE OF ETHYLENE/$g(a)-OLEFIN COPOLYMER AND USE OF ETHYLENE COPOLYMER COMPOSITION Mitsui Chemicals, Inc. (JP) 2001-03-28 EP disclosed
EP-0982362-A1 ETHYLENE COPOLYMER COMPOSITION AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2000-03-01 EP disclosed
US-5840808-A Process for preparing olefin polymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-11-24 US disclosed
EP-0763553-A1 PROCESS FOR PREPARING OLEFIN POLYMER MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-03-19 EP disclosed