Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HARS1 | P12081 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MARS1 | P56192 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL27713160 | 0.82 | CYP3A4 (0.49) | HARS1CYP3A4SLC7A5NLNBTK | |
| SCHEMBL9732187 | 0.78 | ALDH1A1 (0.43) | SLC7A5BTKALDH1A1GSK3B | |
| SCHEMBL1577868 | 0.77 | ADORA2A (0.46) | CYP3A4ALDH1A1MARS1GSK3B | |
| SCHEMBL9663409 | 0.76 | MARS1 (0.58) | ALDH1A1MARS1GSK3B | |
| SCHEMBL4201622 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MARS1GSK3B | |
| SCHEMBL28077123 | 0.75 | NNMT (0.45) | CYP3A4ALDH1A1MARS1GSK3B | |
| SCHEMBL388562 | 0.72 | CYP3A4 (0.73) | CYP3A4SLC7A5ALDH1A1 | |
| SCHEMBL28554819 | 0.71 | CYP3A4 (0.67) | CYP3A4SLC7A5NLNALDH1A1 | |
| SCHEMBL28406873 | 0.71 | ADORA2A (0.50) | CYP3A4ALDH1A1GSK3B | |
| SCHEMBL163444 | 0.71 | CYP3A4 (0.71) | CYP3A4SLC7A5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101574151-A | Nutritional food with function of strengthening immunity and preparation method thereof | BEIJING HUIZHONGMINGJIE BIOTEC (CN) | 2009-11-11 | — | — | CN | disclosed |
| US-6590140-B1 | Transgenic plant which expresses a polypeptide comprising given amino acid sequence; iron uptake; can be used to remove pollutants from soil or as nutritional supplements to treat iron- or zinc-deficiency | TRUSTEES OF DARTMOUTH COLLEGE | 2003-07-08 | — | — | US | disclosed |
| US-6162900-A | Metal-regulated transporters and uses therefor | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2000-12-19 | — | — | US | disclosed |
| US-5846821-A | Metal-regulated transporters and uses therefor | TRUSTEES OF DARTMOUTH COLLEGE (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1997045000-A1 | METAL-REGULATED TRANSPORTERS AND USES THEREFOR | TRUSTEES OF DARTMOUTH COLLEGE (US) | 1997-12-04 | — | — | WO | disclosed |
| CN-1123697-A | Bulaogao for preventing senility | HE YANXUE (CN) | 1996-06-05 | — | — | CN | disclosed |