Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | AHCY | P23526 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ABL2 | P42684 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1577868 | 0.79 | ADORA2A (0.46) | ALDH1A1GSK3BAHCYADORA2AADORA1 | |
| SCHEMBL7197911 | 0.78 | HARS1 (0.50) | ALDH1A1SLC7A5GSK3BBTK | |
| SCHEMBL4201622 | 0.77 | ALDH1A1 (0.42) | ALDH1A1GSK3BEGFRAHCYADORA2A | |
| SCHEMBL28077123 | 0.77 | NNMT (0.45) | ALDH1A1GSK3BAHCY | |
| SCHEMBL10894212 | 0.77 | SLC7A5 (0.38) | SLC7A5 | |
| SCHEMBL14125909 | 0.76 | ADORA2A (0.51) | ALDH1A1GSK3BEGFRAHCYADORA2A | |
| SCHEMBL9663409 | 0.76 | MARS1 (0.58) | ALDH1A1GSK3BDOT1LAHCYADORA2A | |
| SCHEMBL28406876 | 0.75 | ADORA2A (0.50) | ALDH1A1GSK3BEGFRAHCYADORA2A | |
| SCHEMBL528457 | 0.74 | SLC7A5 (0.39) | SLC7A5 | |
| SCHEMBL28406873 | 0.73 | ADORA2A (0.50) | ALDH1A1GSK3BAHCYADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1080306-C | Adjusting and controlling factor for expression of nitrile solution deenzyme and gene thereof | MITSUBISHI RAYON CO (JP) | 2002-03-06 | — | — | CN | disclosed |
| EP-0332216-B1 | NOVEL SUBSTANCE FOR AGRICULTURAL USE AND PROCESS FOR ITS PRODUCTION | Kaken Pharmaceutical Co., Ltd. (JP) | 1992-11-25 | — | — | EP | disclosed |
| US-5102794-A | Culturing and isolating microorganism KITASATOSPORIA | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| US-5032611-A | Rice plant disease prevention | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-07-16 | — | — | US | disclosed |
| EP-0332216-A1 | Novel substance for agricultural use and process for its production | Kaken Pharmaceutical Co., Ltd. (JP) | 1989-09-13 | — | — | EP | disclosed |
| US-4784953-A | NOCARDIA WHICH FORMS 4(3-PROPIONIC ACID-5-HYDROXY-7-METHYL INDANONE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1988-11-15 | — | — | US | disclosed |