Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MARS1 | P56192 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | AHCY | P23526 | 6/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897158 | 0.83 | ALDH1A1 (0.34) | ALDH1A1GSK3BMARS1ADORA2AADORA1 | |
| SCHEMBL1577868 | 0.81 | ADORA2A (0.46) | ALDH1A1GSK3BMARS1ADORA2AADORA1 | |
| SCHEMBL28077123 | 0.79 | NNMT (0.45) | ALDH1A1GSK3BMARS1AHCY | |
| SCHEMBL9663409 | 0.78 | MARS1 (0.58) | ALDH1A1GSK3BMARS1ADORA2AADORA1 | |
| SCHEMBL9732187 | 0.77 | ALDH1A1 (0.43) | ALDH1A1GSK3BADORA2AADORA1AHCY | |
| SCHEMBL28406873 | 0.75 | ADORA2A (0.50) | ALDH1A1GSK3BADORA2AADORA1AHCY | |
| SCHEMBL7197911 | 0.75 | HARS1 (0.50) | ALDH1A1GSK3BMARS1 | |
| SCHEMBL28113155 | 0.74 | GSK3B (0.51) | ALDH1A1GSK3BADORA2AADORA1AHCY | |
| SCHEMBL14125909 | 0.73 | ADORA2A (0.51) | ALDH1A1GSK3BADORA2AADORA1AHCY | |
| SCHEMBL16485904 | 0.72 | GSK3B (0.48) | ALDH1A1GSK3BADORA2AADORA1AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8206931-B2 | Methods of identifying modulators of cellular glycosylation using GTRAP3-18 | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-06-26 | — | — | US | disclosed |
| EP-1595129-A4 | METHODS OF IDENTIFYING MODULATORS OF CELLULAR GLYCOSYLATION USING GTRAP3-18 | UNIV JOHNS HOPKINS (US) | 2009-03-04 | — | — | EP | disclosed |
| US-20060211042-A1 | Methods of identifying modulators of cellular glycosylation using gtrap3-18 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-09-21 | — | — | US | disclosed |
| EP-1595129-A2 | METHODS OF IDENTIFYING MODULATORS OF CELLULAR GLYCOSYLATION USING GTRAP3-18 | THE JOHNS HOPKINS UNIVERSITY (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004065932-A2 | METHODS OF IDENTIFYING MODULATORS OF CELLULAR GLYCOSYLATION USING GTRAP3-18 | THE JOHNS HOPKINS UNIVERSITY (US) | 2004-08-05 | — | — | WO | disclosed |