Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198219 | 0.90 | ALDH1A1 (0.31) | TSHR | |
| SCHEMBL27841202 | 0.81 | ALDH1A1 (0.33) | CES2CES1TSHR | |
| SCHEMBL27895965 | 0.78 | ALDH1A1 (0.31) | TSHR | |
| SCHEMBL2271985 | 0.77 | LTA4H (0.32) | PTGS2LTA4HPCSK9LMNACES2 | |
| SCHEMBL2267192 | 0.74 | GAA (0.33) | LTA4HPCSK9SIGMAR1TDP1 | |
| SCHEMBL2273446 | 0.74 | SIGMAR1 (0.32) | LTA4HPCSK9SIGMAR1 | |
| SCHEMBL417994 | 0.74 | LTA4H (0.38) | PTGS2LTA4HPCSK9CES2CES1 | |
| SCHEMBL114779 | 0.74 | LTA4H (0.38) | PTGS2LTA4HPCSK9CES2CES1 | |
| SCHEMBL10384708 | 0.73 | CYP3A4 (0.30) | TDP1 | |
| SCHEMBL14958525 | 0.73 | RELA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | claimed |
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | disclosed |