SCHEMBL7198474

SCHEMBL7198474

CC(c1ccccc1)c1ccc(C(=O)O)c(C(=O)O)c1C(C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.42
ALDH1A1 P00352 5/20 0.36
ALOX15 P16050 1/20 0.36
VKORC1 Q9BQB6 1/20 0.36
FABP3 P05413 1/20 0.36
FABP4 P15090 1/20 0.36
ACE2 Q9BYF1 1/20 0.36
KDM4C Q9H3R0 1/20 0.35
MAPT P10636 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 3/20 0.35
ASPH Q12797 2/20 0.35
KDM8 Q8N371 2/20 0.35
AKR1C3 P42330 1/20 0.34
HSD17B10 Q99714 2/20 0.34
CDC25A P30304 1/20 0.34
CDC25B P30305 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10583690 0.84 TYR (0.46) TYRALDH1A1ALOX15VKORC1ACE2
SCHEMBL28566236 0.83 ALDH1A1 (0.42) TYRALDH1A1ALOX15VKORC1ACE2
SCHEMBL28549725 0.83 ALDH1A1 (0.42) TYRALDH1A1ALOX15VKORC1ACE2
SCHEMBL27749720 0.81 TYR (0.42) TYRALDH1A1ALOX15FABP3FABP4
SCHEMBL27749718 0.81 TYR (0.42) TYRALDH1A1ALOX15FABP3FABP4
SCHEMBL7201769 0.80 ALDH1A1 (0.44) TYRALDH1A1ALOX15MAPTHDAC8
SCHEMBL16672620 0.78 CRHBP (0.38) TYRALDH1A1ACE2HDAC8GAA
SCHEMBL584940 0.77 ALDH1A1 (0.55) TYRALDH1A1ALOX15KDM4CMAPT
SCHEMBL18641007 0.76 GRM1 (0.42) TYRALDH1A1ALOX15ACE2MAPT
SCHEMBL28238364 0.75 CYP1A2 (0.42) ALDH1A1ALOX15FABP3FABP4ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003078377-A1 OXIDATION OF O-XYLOL TO FORM O-TOLUIC AND OTHER OXIDATION PRODUCTS BY THE CONTROLLED SUPPLY OF AN OXYGEN-CONTAINING GAS BASF AKTIENGESELLSCHAFT (DE) 2003-09-25 WO disclosed
WO-2003078369-A1 OXIDATION OF O-XYLOL TO FORM O-TOLUIC ACID AND OTHER OXIDATION PRODUCTS BY THE STAGGERED SUPPLY OF AN OXYGEN-CONTAINING GAS BASF AKTIENGESELLSCHAFT (DE) 2003-09-25 WO disclosed