Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505530 | 0.88 | L3MBTL1 (0.61) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL7197465 | 0.85 | LMNA (0.42) | TDP1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL7202862 | 0.84 | L3MBTL1 (0.55) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL7199609 | 0.83 | LMNA (0.60) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL7198885 | 0.83 | CES2 (0.47) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL11812978 | 0.83 | LMNA (0.47) | TDP1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL6289187 | 0.80 | ALDH1A1 (0.46) | TDP1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL16781997 | 0.80 | L3MBTL1 (0.73) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL14519387 | 0.80 | L3MBTL1 (0.49) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL7200938 | 0.79 | TDP1 (0.50) | TDP1L3MBTL1CES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003042148-A2 | PROCESS FOR PRODUCING BISBENZIL COMPOUNDS | SHOWA DENKO K. K. (JP) | 2003-05-22 | — | — | WO | disclosed |