Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 5/20 | 0.59 |
| ▸ | THRB | P10828 | 3/20 | 0.59 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7193935 | 0.99 | THRA (0.57) | THRATHRBLTB4RPLA2G4BSMPD1 | |
| SCHEMBL7198598 | 0.96 | THRB (0.53) | THRATHRBLTB4RPLA2G4BSMPD1 | |
| SCHEMBL7196312 | 0.92 | KMT2A (0.52) | THRATHRBLTB4RPLA2G4BKMT2A | |
| SCHEMBL7189188 | 0.91 | THRA (0.64) | THRATHRBLTB4RPLA2G4BSMPD1 | |
| SCHEMBL7192558 | 0.90 | PLA2G2A (0.50) | THRATHRBLTB4RPLA2G4B | |
| SCHEMBL7194180 | 0.90 | THRA (0.62) | THRATHRBLTB4RPLA2G4BSMPD1 | |
| SCHEMBL7193969 | 0.89 | PLA2G2A (0.48) | THRATHRBLTB4RKMT2A | |
| SCHEMBL7193665 | 0.88 | THRB (0.58) | THRATHRBLTB4RPLA2G4BSMPD1 | |
| SCHEMBL7188095 | 0.85 | THRA (0.43) | THRATHRBLTB4R | |
| SCHEMBL7193490 | 0.85 | FOS (0.46) | THRATHRBKMT2ANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | STATENS SERUM INSTITUTE (DK) | 2003-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | AKR1C3, AKR1C1, AKR1A1 | THRA 2660/4885THRB 2309/4885LTB4R 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.