SCHEMBL7199284

SCHEMBL7199284

CC(C)(C)c1ccc(N2NC(c3ccccc3)=C(c3ccccc3)O2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.34
ALOX15 P16050 2/20 0.33
POLB P06746 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD11B1 P28845 2/20 0.33
TSHR P16473 2/20 0.32
NR1H4 Q96RI1 1/20 0.32
PMM2 O15305 1/20 0.32
MPI P34949 1/20 0.32
PHOSPHO1 Q8TCT1 1/20 0.32
GAA P10253 1/20 0.32
LMNA P02545 3/20 0.32
TYR P14679 1/20 0.32
TP53 P04637 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL58583 0.84 GAA (0.39) MDM2ALOX15ALDH1A1HSD17B10KDM4E
SCHEMBL360183 0.70 CYP19A1 (0.40) MDM2ALOX15POLBALDH1A1HSD17B10
SCHEMBL1816648 0.65 AVPR1A (0.54) ALDH1A1HSD17B10KDM4EHPGDKMT2A
SCHEMBL128222 0.65 KIF11 (0.59) ALDH1A1TSHRLMNATYRNPC1
SCHEMBL3421942 0.65 KIF11 (0.59) ALDH1A1TSHRLMNATYRNPC1
Ethane SCHEMBL27903947 0.63 KIF11 (0.57) ALDH1A1TSHRLMNATYRNPC1
SCHEMBL15347565 0.63 AVPR1A (0.60) ALDH1A1HSD17B10KDM4EHPGDTSHR
Biphenyl SCHEMBL27660679 0.62 ALDH1A1 (0.53) ALOX15ALDH1A1TSHRLMNATYR
P-Xylene SCHEMBL1419675 0.62 TSHR (0.68) POLBALDH1A1HPGDTDP1KMT2A
Biphenyl SCHEMBL7702949 0.62 LMNA (0.73) ALDH1A1HSD17B10HPGDTDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6593013-B2 Producing a cyclic azine dye by reacting a phenylenediamine derivative with a phenol derivative in the presence of an oxidizing agent in an alkaline atmosphere FUJI PHOTO FILM CO., LTD. (JP) 2003-07-15 US disclosed
US-20020102435-A1 Electroluminescence device, cyclic azine compound and production process of cyclic azine dye FUJI PHOTO FILM CO., LTD. 2002-08-01 US disclosed
US-6379823-B1 BENZO(A)PHENAZINE, BENZO(A)PHENOXAZINE, OR BENZO(A)PHENOTHIAZINE DERIVATIVE FLUORESCENT DYES; DURABILITY; EMITS RED LIGHT IN HIGH COLOR PURITY; BRIGHTNESS FUJI PHOTO FILM CO., LTD. (JP) 2002-04-30 US disclosed