SCHEMBL360183

SCHEMBL360183

CC(C)(C)c1ccc(C2=CNN(c3ccc(-c4ccccc4)cc3)O2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.40
KIF11 P52732 3/20 0.36
PTGES O14684 1/20 0.36
ALOX5 P09917 1/20 0.36
MDM2 Q00987 1/20 0.33
KMT2A Q03164 1/20 0.33
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
FAAH O00519 1/20 0.33
MGLL Q99685 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16781955 0.88 FAAH (0.40) KMT2AKDM4EALDH1A1HPGDALOX15
SCHEMBL6152868 0.74 ALDH1A1 (0.38) ALDH1A1POLB
SCHEMBL128222 0.72 KIF11 (0.59) CYP19A1KIF11ALDH1A1HDAC6CYP2C9
SCHEMBL3421942 0.72 KIF11 (0.59) CYP19A1KIF11ALDH1A1HDAC6CYP2C9
SCHEMBL27580116 0.71 CYP19A1 (0.37) CYP19A1KIF11PTGESALOX5MDM2
SCHEMBL6130767 0.71 ALDH1A1 (0.38) ALDH1A1POLB
Ethane SCHEMBL27903947 0.70 KIF11 (0.57) CYP19A1KIF11ALDH1A1HDAC6CYP2C9
SCHEMBL7199284 0.70 MDM2 (0.34) KIF11MDM2KMT2ATNKSTNKS2
SCHEMBL3664594 0.67 LMNA (0.70) KIF11KMT2AALDH1A1HPGDHSD17B10
SCHEMBL18801808 0.66 KIF11 (0.53) CYP19A1KIF11ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060255322-A1 Methods and compositions for improved electrophoretic display performance WU ZARNG-ARH G 2006-11-16 US claimed
US-20040085619-A1 Novel Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. 2004-05-06 US claimed
CN-1791655-B Organic phosphorescent material and organic optoelectronic device ISIS INNOVATION 2014-06-25 CN disclosed
US-8547628-B2 Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. (US) 2013-10-01 US disclosed
US-8179589-B2 Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. (US) 2012-05-15 US disclosed
US-20120013971-A1 METHODS AND COMPOSITIONS FOR IMPROVED ELECTROPHORETIC DISPLAY PERFORMANCE E INK CALIFORNIA, LLC 2012-01-19 US disclosed
US-20100301280-A1 METHODS AND COMPOSITIONS FOR IMPROVED ELECTROPHORETIC DISPLAY PERFORMANCE SIPIX IMAGING INC. 2010-12-02 US disclosed
US-7800813-B2 Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. (US) 2010-09-21 US disclosed
US-7347957-B2 Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. (US) 2008-03-25 US disclosed
US-20070152196-A1 METHODS AND COMPOSITIONS FOR IMPROVED ELECTROPHORETIC DISPLAY PERFORMANCE E INK CORPORATION 2007-07-05 US disclosed
US-20060255322-A1 Methods and compositions for improved electrophoretic display performance WU ZARNG-ARH G 2006-11-16 US disclosed
US-20060166033-A1 Polymerizable, luminescent compounds and mixtures, luminescent polymer materials and their use MERCK PATENT GMBH (DE) 2006-07-27 US disclosed
CN-1791655-A Organic phosphorescent material and organic optoelectronic device ISIS INNOVATION (GB) 2006-06-21 CN disclosed
US-20050244718-A1 Polymerizable, luminescent compounds and mixtures, luminescent polymer materials and their use MERCK PATENT GMBH (DE) 2005-11-03 US disclosed
EP-1529242-A2 PROTECTING LAYER WITH ADDITIVES FOR ELECTROPHORETIC DISPLAY, METHOD OF PROVIDING SUCH LAYER, AND ELECTROPHORETIC DISPLAY WITH SUCH A LAYER Sipix Imaging, Inc. (US) 2005-05-11 EP disclosed
US-20050007648-A1 Methods and compositions for improved electrophoretic display performance E INK CORPORATION 2005-01-13 US disclosed
US-20040085619-A1 Novel Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. 2004-05-06 US disclosed
WO-2004010206-A2 PROTECTING LAYER WITH ADDITIVES FOR ELECTROPHORETIC DISPLAY, METHOD OF PROVIDING SUCH LAYER, AND ELECTROPHORETIC DISPLAY WITH SUCH A LAYER SIPIX IMAGING, INC. (US) 2004-01-29 WO disclosed