SCHEMBL7199378

SCHEMBL7199378

C=CCOC(=O)C(C)CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.42
TSHR P16473 2/20 0.38
CASP1 P29466 13/20 0.38
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7194323 0.84 TDP1 (0.50) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL21989095 0.82 TDP1 (0.41) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL8909065 0.81 CYP1A2 (0.50) TDP1TSHRCYP3A4MAPT
3-Methylbutanoic Acid SCHEMBL9561318 0.79 TDP1 (0.42) TDP1TSHRCASP1CYP3A4MAPT
SCHEMBL1289265 0.79 TDP1 (0.44) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL9283778 0.79 TDP1 (0.44) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL11213886 0.79 TDP1 (0.44) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL27587694 0.78 TDP1 (0.38) TDP1TSHRCASP1CYP3A4MAPT
SCHEMBL13908443 0.78 TDP1 (0.43) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL28099722 0.78 TDP1 (0.47) TDP1TSHRCYP3A4MAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11913049-B2 Bioconversion of short-chain hydrocarbons to fuels and chemicals Gonzalez, Ramon (US) 2024-02-27 US claimed
US-20200347423-A1 Bioconversion of Short-Chain Hydrocarbons to Fuels and Chemicals GONZALEZ, RAMON 2020-11-05 US claimed
US-20180355394-A1 BIOCONVERSION OF SHORT-CHAIN HYDROCARBONS TO FUELS AND CHEMICALS GONZALES RAMON (US) 2018-12-13 US claimed
WO-2016161043-A1 BIOCONVERSION OF SHORT-CHAIN HYDROCARBONS TO FUELS AND CHEMICALS WILLIAM MARSH RICE UNIVERSITY (US) 2016-10-06 WO claimed
JP-7258149-A None JP disclosed
US-11913049-B2 Bioconversion of short-chain hydrocarbons to fuels and chemicals Gonzalez, Ramon (US) 2024-02-27 US disclosed
US-20200347423-A1 Bioconversion of Short-Chain Hydrocarbons to Fuels and Chemicals GONZALEZ, RAMON 2020-11-05 US disclosed
US-20180355394-A1 BIOCONVERSION OF SHORT-CHAIN HYDROCARBONS TO FUELS AND CHEMICALS GONZALES RAMON (US) 2018-12-13 US disclosed
US-20170087205-A1 Replacement Therapy for Natriuretic Peptide Deficiencies PALATIN TECHNOLOGIES INC (US) 2017-03-30 US disclosed
US-20160354443-A1 Replacement Therapy for Natriuretic Peptide Deficiencies PALATIN TECHNOLOGIES INC (US) 2016-12-08 US disclosed
WO-2016161043-A1 BIOCONVERSION OF SHORT-CHAIN HYDROCARBONS TO FUELS AND CHEMICALS WILLIAM MARSH RICE UNIVERSITY (US) 2016-10-06 WO disclosed
US-8828926-B2 Uses of natriuretic peptide constructs PALATIN TECHNOLOGIES, INC. (US) 2014-09-09 US disclosed
US-8580746-B2 Amide linkage cyclic natriuretic peptide constructs PALATIN TECHNOLOGIES, INC. (US) 2013-11-12 US disclosed
US-20130274207-A9 Uses of Natriuretic Peptide Constructs PALATIN TECHNOLOGIES, INC. (US) 2013-10-17 US disclosed
US-20130045928-A1 Uses of Natriuretic Peptide Constructs PALATIN TECHNOLOGIES, INC. (US) 2013-02-21 US disclosed
US-20110263818-A1 Peptidic Constructs with Amino Acid Surrogates PALATIN TECHNOLOGIES, INC. (US) 2011-10-27 US disclosed
US-20100035821-A1 Amide Linkage Cyclic Natriuretic Peptide Constructs PALATIN TECHNOLOGIES, INC. (US) 2010-02-11 US disclosed
WO-2003010566-A2 PLASTIC LENS MATERIAL, PLASTIC LENS COMPOSITION, PLASTIC LENS OBTAINED BY CURING THE COMPOSITION AND PROCESS FOR PRODUCING THE PLASTIC LENS SHOWA DENKO K. K. (JP) 2003-02-06 WO disclosed
JP-H07258149-A PRODUCTION OF 2-METHYLSUCCINIC ACID KURARAY CO LTD 1995-10-09 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263818-A1 Peptidic Constructs with Amino Acid Surrogates ARGLU1, QRFPR, ARG1 TDP1 3303/4885TSHR 111/4885CASP1 3288/4885
US-20130045928-A1 Uses of Natriuretic Peptide Constructs NPR1, NPPA, NPR3 TDP1 2773/4885TSHR 227/4885CASP1 2428/4885
US-20170087205-A1 Replacement Therapy for Natriuretic Peptide Deficiencies NPR1, NPR3, NPPA TDP1 2232/4885TSHR 102/4885CASP1 4750/4885
US-20100035821-A1 Amide Linkage Cyclic Natriuretic Peptide Constructs NPR1, NPR3, NPPA TDP1 3851/4885TSHR 63/4885CASP1 4668/4885
US-20130274207-A9 Uses of Natriuretic Peptide Constructs NPR1, NPPA, NPR3 TDP1 2773/4885TSHR 227/4885CASP1 2428/4885
US-20160354443-A1 Replacement Therapy for Natriuretic Peptide Deficiencies NPR1, NPR3, NPPA TDP1 2232/4885TSHR 102/4885CASP1 4750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.