Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628315 | 0.80 | ITGB1 (0.57) | ITGB1ITGA4NPSR1POLBKMT2A | |
| SCHEMBL6629685 | 0.79 | ITGA4 (0.66) | ITGB1ITGA4KMT2A | |
| SCHEMBL8586015 | 0.77 | ALDH1A1 (0.52) | ITGB1ITGA4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5523971 | 0.77 | ALDH1A1 (0.46) | ITGB1ITGA4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6626906 | 0.77 | ALDH1A1 (0.48) | ITGB1ITGA4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6627416 | 0.76 | ITGB1 (0.47) | ITGB1ITGA4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4886593 | 0.75 | ITGB1 (0.51) | ITGB1ITGA4ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL5659226 | 0.74 | SMN1; SMN2 (0.76) | KDM4EMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13984251 | 0.74 | SMN1; SMN2 (0.76) | KDM4EMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4868046 | 0.74 | TDP1 (0.52) | ALDH1A1TDP1POLBTSHRNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030109459-A1 | N-alkanoylphenylalamine derivatives | CHEN LI (US) | 2003-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109459-A1 | N-alkanoylphenylalamine derivatives | VCAM1, ICAM1, SELL | ITGB1 14/4885ITGA4 9/4885KDM4E 1229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.