Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044047 | 0.76 | HTR1A (0.31) | — | |
| SCHEMBL1029280 | 0.75 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL7524851 | 0.73 | ACHE (0.36) | ACHEPARP1PARP10PARP11ALDH1A1 | |
| SCHEMBL2052193 | 0.72 | ACHE (0.47) | ACHEPARP1PARP10PARP11ALDH1A1 | |
| SCHEMBL4468060 | 0.67 | CA2 (0.32) | — | |
| SCHEMBL6142471 | 0.66 | POLB (0.31) | — | |
| SCHEMBL714734 | 0.66 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL4650969 | 0.65 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL135721 | 0.64 | PNMT (0.53) | ACHEPARP1PARP10PARP11ALDH1A1 | |
| SCHEMBL2960382 | 0.63 | ALDH1A1 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1297027-A1 | SILOXY SUBSTITUTED COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002000738-A1 | SILOXY SUBSTITUTED COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2002-01-03 | — | — | WO | disclosed |