Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7201366 | 0.91 | GPR3 (0.45) | CYP1A2MEN1MAPTKMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL7198761 | 0.89 | CA12 (0.46) | CYP1A2MEN1MAPTKMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL27745820 | 0.78 | CYP1A1 (0.45) | CYP1A2MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL8896192 | 0.77 | MEN1 (0.52) | CYP1A2MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL11384034 | 0.75 | CYP1A2 (0.46) | CYP1A2MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL30818407 | 0.69 | GPR3 (0.46) | CYP1A2MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL9449351 | 0.69 | HRH3 (0.51) | CYP1A2MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL1134724 | 0.69 | ALDH1A1 (0.64) | CYP1A2MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL346790 | 0.69 | ALDH1A1 (0.64) | CYP1A2MEN1MAPTKMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL8644114 | 0.68 | MEN1 (0.43) | CYP1A2MEN1MAPTKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942006-B1 | Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst | TOSOH CORP (JP) | 2003-06-04 | — | — | EP | disclosed |