Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645107 | 0.86 | KCNA5 (0.39) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL6645963 | 0.85 | ALDH1A1 (0.39) | KMT2ACYP3A4ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL6645358 | 0.84 | GPR27 (0.37) | MEN1KMT2AALDH1A1CYP2C19TDP1 | |
| SCHEMBL6645258 | 0.80 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL7201167 | 0.79 | THRB (0.40) | MEN1KMT2ACYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL6648929 | 0.77 | TAS1R3 (0.42) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL6644367 | 0.76 | DGAT1 (0.35) | GPR27NR3C1TRPV4 | |
| SCHEMBL7201171 | 0.75 | SCD (0.43) | KMT2AALDH1A1TDP1MAPTRAB9A | |
| SCHEMBL6644541 | 0.74 | DGAT1 (0.37) | KMT2AALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL6645551 | 0.74 | KMT2A (0.38) | MEN1KMT2AALDH1A1GPR27LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | MEN1 3820/4885KMT2A 916/4885CYP3A4 2434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.