Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.54 |
| ▸ | FEN1 | P39748 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.51 |
| ▸ | WNT3A | P56704 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15979664 | 0.87 | ALDH1A1 (0.68) | L3MBTL1TP53ALDH1A1MAPTTDP1 | |
| SCHEMBL7207201 | 0.83 | RAB9A (0.70) | L3MBTL1TP53ALDH1A1MAPTGSK3B | |
| SCHEMBL711360 | 0.82 | RAB9A (0.75) | L3MBTL1ALDH1A1TDP1GSK3BERCC5 | |
| SCHEMBL29987169 | 0.82 | ERCC5 (0.74) | ALDH1A1MAPTERCC5FEN1MEN1 | |
| SCHEMBL7203396 | 0.81 | CTNNB1 (0.77) | L3MBTL1TP53ALDH1A1MAPTGSK3B | |
| SCHEMBL9821675 | 0.80 | TP53 (0.66) | L3MBTL1TP53ALDH1A1MAPTTDP1 | |
| SCHEMBL30421622 | 0.80 | TP53 (0.66) | L3MBTL1TP53ALDH1A1MAPTTDP1 | |
| SCHEMBL7201436 | 0.79 | CTNNB1 (0.78) | L3MBTL1ALDH1A1MAPTGSK3BERCC5 | |
| SCHEMBL7203112 | 0.76 | RAB9A (0.54) | L3MBTL1TP53ALDH1A1MAPTGSK3B | |
| SCHEMBL1436183 | 0.76 | ERCC5 (0.66) | L3MBTL1ALDH1A1MAPTTDP1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605730-B2 | 3-(2-Thienyl)-5-phenyl-1H-pyrazole compounds of given formula | NIHON BAYER AGROCHEM K.K. (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20030028034-A1 | Nematicidal pyrazoles | WADA KATSUAKI (JP) | 2003-02-06 | — | — | US | disclosed |
| US-6310049-B1 | 3-(2-THIENYL),5-(SUBSTITUTED PHENYL)-1H-PYRAZOLES AND 3-(SUBSTITUTED PHENYL),5-(2-THIENYL)-1H-PYRAZOLES OF GIVEN FORMULA; ANTHELMINTICS | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028034-A1 | Nematicidal pyrazoles | CBR3, CBR1, CCR4 | L3MBTL1 324/4885TP53 4681/4885ALDH1A1 1476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.