Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 5/20 | 0.44 |
| ▸ | THRB | P10828 | 5/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709945 | 0.87 | THRA (0.48) | THRATHRBHSP90AA1HSP90AB1HPGD | |
| SCHEMBL4596232 | 0.86 | ALDH1A1 (0.47) | HSP90AA1HSP90AB1GABRA1GABRB2ALDH1A1 | |
| SCHEMBL131117 | 0.85 | BCHE (0.47) | THRATHRBHSP90AA1HSP90AB1GABRA1 | |
| SCHEMBL2305253 | 0.81 | TDP1 (0.49) | THRBALDH1A1HIF1AALOX12ALOX15 | |
| SCHEMBL224395 | 0.78 | ALOX12 (0.59) | HSP90AA1HSP90AB1GABRA1GABRB2ALDH1A1 | |
| SCHEMBL31655440 | 0.78 | ALOX12 (0.59) | HSP90AA1HSP90AB1GABRA1GABRB2ALDH1A1 | |
| SCHEMBL3152462 | 0.78 | GAA (0.62) | HSP90AA1HSP90AB1GABRA1GABRB2ALDH1A1 | |
| SCHEMBL68663 | 0.78 | ESR1 (0.47) | ALOX15TP53CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4596216 | 0.77 | TYR (0.45) | GAAHTTTYRALOX15HPGD | |
| SCHEMBL4390370 | 0.77 | GABRA1 (0.48) | HSP90AA1HSP90AB1GABRA1GABRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603035-B1 | A method for producing a high purity cyanate comprising reacting a phenol compound represented by the following formula | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-08-05 | — | — | US | disclosed |