SCHEMBL7202308

SCHEMBL7202308

C=CCN(CC=C)Sc1ccc(C(=O)c2ccc(SN(CC=C)CC=C)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LSS P48449 12/20 0.41
LMNA P02545 5/20 0.39
ALDH1A1 P00352 5/20 0.39
HPGD P15428 4/20 0.39
MAPT P10636 2/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
SRD5A2 P31213 1/20 0.34
PKM P14618 1/20 0.34
HTT P42858 1/20 0.34
ALOX12 P18054 1/20 0.33
CCR6 P51684 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL611208 0.76 HPGD (0.46) LMNAALDH1A1HPGDMAPTESR1
SCHEMBL24893820 0.76 SMN1; SMN2 (0.42) LSSLMNASMN1; SMN2L3MBTL1
SCHEMBL88637 0.72 HPGD (0.52) LSSLMNAALDH1A1HPGDMAPT
SCHEMBL11297704 0.71 AKR1C3 (0.42) LSSLMNAALDH1A1HPGDMAPT
SCHEMBL3448940 0.70 THRA (0.41) LMNAALDH1A1HPGDMAPTGAA
SCHEMBL610429 0.70 ALDH1A1 (0.57) LMNAALDH1A1HPGDMAPTSRD5A2
SCHEMBL19696453 0.69 HPGD (0.53) LSSLMNAALDH1A1HPGDMAPT
SCHEMBL25360355 0.69 LMNA (0.42) LMNAALDH1A1HPGDMAPTESR1
SCHEMBL196732 0.69 HPGD (0.52) LMNAALDH1A1HPGDMAPTESR1
SCHEMBL11327615 0.67 ALDH1A1 (0.62) LSSLMNAALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3679343-B1 COUPON DESIGN FOR ENHANCED COLOR SENSITIVITY FOR COLORIMETRIC-BASED CHEMICAL ANALYSIS OF LIQUIDS UNIV CLEMSON RES FOUNDATION (US) 2023-06-07 EP disclosed
US-20210364444-A1 Coupon Design for Enhanced Color Sensitivity for Colorimetric-Based Chemical Analysis of Liquids UNIV CLEMSON RES FOUNDATION (US) 2021-11-25 US disclosed
EP-3679343-A1 COUPON DESIGN FOR ENHANCED COLOR SENSITIVITY FOR COLORIMETRIC-BASED CHEMICAL ANALYSIS OF LIQUIDS Clemson University Research Foundation (US) 2020-07-15 EP disclosed
WO-2019050837-A1 COUPON DESIGN FOR ENHANCED COLOR SENSITIVITY FOR COLORIMETRIC-BASED CHEMICAL ANALYSIS OF LIQUIDS CLEMSON UNIVERSITY RESEARCH FOUNDATION (US) 2019-03-14 WO disclosed
US-6541269-B1 Colorimetric test strips INDUSTRIAL TEST SYSTEMS, INC. 2003-04-01 US disclosed