Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202999 | 1.00 | SIRT1 (0.42) | SIRT1PYGLMMP3CTSSCTSL | |
| SCHEMBL7205858 | 0.83 | CTSS (0.47) | CTSSCTSLCTSBCTSKMMP9 | |
| SCHEMBL7205866 | 0.83 | CTSS (0.47) | CTSSCTSLCTSBCTSKMMP9 | |
| Hydrochloric Acid SCHEMBL7203602 | 0.83 | PYGL (0.42) | PYGLMMP3MMP9MMP8MMP14 | |
| Hydrochloric Acid SCHEMBL7203605 | 0.83 | PYGL (0.42) | PYGLMMP3MMP9MMP8MMP14 | |
| SCHEMBL7203966 | 0.79 | MMP9 (0.53) | PYGLMMP3MMP9MMP8MMP14 | |
| SCHEMBL7203960 | 0.79 | MMP9 (0.53) | PYGLMMP3MMP9MMP8MMP14 | |
| SCHEMBL7204605 | 0.78 | MMP9 (0.44) | PYGLMMP3MMP9MMP8MMP14 | |
| SCHEMBL7204595 | 0.78 | MMP9 (0.44) | PYGLMMP3MMP9MMP8MMP14 | |
| SCHEMBL7207304 | 0.77 | KMT2A (0.53) | PYGLMMP3MMP9MMP8MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921122-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-6110967-A | USEFUL AS AGENTS FOR PREVENTING AND TREATING METABOLIC OSTEOPATHY SUCH AS OSTEOPOROSIS, HYPERCALCEMIA AND BONE METASTASIS OF CANCER BECAUSE THEY SPECIFICALLY INHIBITS CATHEPSIN L AND ITS FAMILY ENZYMES TO INHIBIT BONE RESORPTION | TAIHO PHARMACEUTICALS CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |