Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29612278 | 1.00 | KIF11 (0.34) | KIF11BRD4CREBBPKDM4EALDH1A1 | |
| SCHEMBL30621324 | 0.97 | BRD4 (0.34) | KIF11BRD4CREBBPKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4556847 | 0.87 | KIF11 (0.35) | KIF11RAB9ASMN1; SMN2PARP1 | |
| Hydrochloric Acid SCHEMBL16394004 | 0.87 | RXRB (0.33) | KIF11S1PR1 | |
| Hydrochloric Acid SCHEMBL6889130 | 0.85 | SYK (0.33) | ALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL31571607 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL27495381 | 0.84 | PDCD1 (0.33) | BRD4CREBBPALDH1A1 | |
| Hydrochloric Acid SCHEMBL6065907 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL7934283 | 0.84 | MAOA (0.32) | ALDH1A1TSHRNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3163965 | 0.83 | PDCD1 (0.35) | BRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116234671-A | Method for producing skin/foam/skin structures with high surface finish | 道达尔能源一技术比利时公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-112154163-B | Transition metal compound and method for preparing polypropylene using the same | LG化学株式会社 | 2022-12-27 | — | — | CN | disclosed |
| CN-110167973-B | High purity polypropylene for molding and polypropylene composition | 道达尔研究技术弗吕公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114401977-A | Transition metal compound and catalyst composition comprising the same | 株式会社LG化学 | 2022-04-26 | — | — | CN | disclosed |
| CN-112154163-A | Novel transition metal compound and method for preparing polypropylene using the same | LG化学株式会社 | 2020-12-29 | — | — | CN | disclosed |
| EP-3735442-A1 | SINGLE-SITE CATALYST BASED IMPACTED COPOLYMERS WITH EXCELLENT MECHANICAL AND OPTICAL PROPERTIES | Borealis AG (AT) | 2020-11-11 | — | — | EP | disclosed |
| WO-2019134951-A1 | SINGLE-SITE CATALYST BASED IMPACTED COPOLYMERS WITH EXCELLENT MECHANICAL AND OPTICAL PROPERTIES | BOREALIS AG (AT) | 2019-07-11 | — | — | WO | disclosed |
| CN-103012623-B | Metalloscene catalyst, its synthesis and purposes in olefin polymerization | NOVOLEN TECH HOLDINGS CV (DE) | 2015-09-16 | — | — | CN | disclosed |
| EP-1828266-B1 | SUPPORTED METALLOCENE CATALYST COMPOSITIONS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2015-07-22 | — | — | EP | disclosed |
| CN-104023934-A | MULTILAYERED ROTOMOULDED ARTICLES COMPRISING A LAYER OF POLYESTER | TOTAL PETROCHEMICALS RES FELUY | 2014-09-03 | — | — | CN | disclosed |
| CN-101384624-B | Catalyst composition for olefin polymerization | NOVOLEN TECH HOLDINGS CV | 2012-07-04 | — | — | CN | disclosed |
| CN-101124252-B | Metallocene catalysts, their synthesis and use in olefin polymerization | NOVOLEN TECH HOLDINGS CV | 2011-10-05 | — | — | CN | disclosed |
| CN-1946748-B | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV | 2011-04-06 | — | — | CN | disclosed |
| CN-101384624-A | Catalyst composition for olefin polymerization | NOVOLEN TECH HOLDINGS CV (NL) | 2009-03-11 | — | — | CN | disclosed |
| CN-101124252-A | Metallocene catalysts, their synthesis and use in olefin polymerization | NOVOLEN TECH HOLDINGS CV (NL) | 2008-02-13 | — | — | CN | disclosed |
| CN-1946748-A | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV (NL) | 2007-04-11 | — | — | CN | disclosed |
| US-20030236378-A1 | For producing propylene polymers that are suited for fiber spinning | BASELL POLYOLEFINE GMBH (DE) | 2003-12-25 | — | — | US | disclosed |
| US-20010007009-A1 | Transition metal catalyzed polymerization of olefinic monomers in a water-containing polymerization medium | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-05 | — | — | US | disclosed |
| EP-0968158-A1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | Basell Polyolefine GmbH (DE) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998040331-A1 | PREPARATION OF PREPARING SUBSTITUTED INDANONES | TARGOR GMBH (DE) | 1998-09-17 | — | — | WO | disclosed |