SCHEMBL7203750

SCHEMBL7203750

O=Cc1ccc(S(=O)(=O)c2cccc3ccccc23)cc1

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 7/20 0.66
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
NAMPT P43490 1/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
AKR1B1 P15121 1/20 0.43
MAOA P21397 1/20 0.42
LOX P28300 1/20 0.42
F2 P00734 2/20 0.41
PRSS1 P07477 2/20 0.41
PRSS2 P07478 2/20 0.41
PRSS3 P35030 2/20 0.41
CYP2D6 P10635 1/20 0.41
HDAC1 Q13547 1/20 0.40
LOXL2 Q9Y4K0 2/20 0.40
ERN1 O75460 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3249669 0.82 HTR6 (0.73) HTR6CA1CA2CA9MEN1
SCHEMBL6828570 0.79 HTR6 (0.70) HTR6CA1CA2CA9NAMPT
SCHEMBL9413714 0.79 HTR6 (0.70) HTR6CA1CA2CA9NAMPT
SCHEMBL10775871 0.79 HTR6 (1.00) HTR6CA1CA2CA9NAMPT
SCHEMBL9587035 0.79 HTR6 (0.70) HTR6CA1CA2CA9MEN1
SCHEMBL7542017 0.79 HTR6 (0.41) HTR6CYP2D6
SCHEMBL7540130 0.78 HTR6 (0.44) HTR6CA1CA2CA9MEN1
SCHEMBL10451361 0.78 HTR6 (0.68) HTR6CA1CA2CA9NAMPT
SCHEMBL547461 0.78 CA1 (0.68) HTR6CA1CA2CA9MEN1
SCHEMBL7198914 0.78 LDHA (0.53) HTR6CYP2D6ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 HTR6 2178/4885CA1 1889/4885CA2 1428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.