Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207934 | 0.76 | MPO (0.41) | TAAR1HTR2AKDM4E | |
| SCHEMBL3042346 | 0.75 | SRD5A2 (0.50) | ALDH1A1TAAR1LTA4HIDO1KDM4E | |
| SCHEMBL26799201 | 0.75 | PTPN5 (0.42) | ALDH1A1TAAR1PTPN5IDO1KDM4E | |
| SCHEMBL13331472 | 0.73 | MEN1 (0.47) | ALDH1A1KDM4E | |
| SCHEMBL28291649 | 0.73 | NSD2 (0.48) | MBOAT4TAAR1LTA4HIDO1 | |
| SCHEMBL7205059 | 0.72 | TAAR1 (0.50) | MBOAT4TAAR1LTA4HIDO1 | |
| SCHEMBL22288569 | 0.71 | TAAR1 (0.46) | MBOAT4TAAR1LTA4HIDO1 | |
| SCHEMBL7111350 | 0.69 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6692367 | 0.69 | AGER (0.50) | — | |
| SCHEMBL26799180 | 0.68 | ALDH1A1 (0.48) | ALDH1A1PTPN5IDO1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003076388-A2 | BIS-ANILINE DERIVATIVES USEFUL AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2003-09-18 | — | — | WO | disclosed |