SCHEMBL7204294

SCHEMBL7204294

CCCCCCCCCCCCCC(=O)OC[C@H](CO)OP(=O)(O)OCCN

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 3/20 0.56
PRKCE Q02156 1/20 0.56
PRKCQ Q04759 1/20 0.56
PRKCD Q05655 1/20 0.56
ENPP2 Q13822 5/20 0.55
LPAR3 Q9UBY5 5/20 0.54
LPAR1 Q92633 4/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
FABP3 P05413 1/20 0.54
LPAR6 P43657 1/20 0.51
LPAR4 Q99677 1/20 0.51
LPAR5 Q9H1C0 1/20 0.51
LPAR2 Q9HBW0 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6254776 1.00 PRKCA (0.56) PRKCAPRKCEPRKCQPRKCDENPP2
SCHEMBL14659956 1.00 PRKCA (0.56) PRKCAPRKCEPRKCQPRKCDENPP2
SCHEMBL1402383 0.94 ENPP2 (0.59) ENPP2LPAR3LPAR1SMN1; SMN2FABP3
SCHEMBL15526366 0.94 ENPP2 (0.59) ENPP2LPAR3LPAR1SMN1; SMN2FABP3
SCHEMBL2126025 0.94 PRKCE (0.61) PRKCAPRKCEPRKCQPRKCDENPP2
SCHEMBL19629017 0.88 ENPP2 (0.57) ENPP2LPAR3LPAR1SMN1; SMN2FABP3
SCHEMBL16714278 0.87 ENPP2 (0.64) ENPP2LPAR3LPAR1
SCHEMBL190727 0.87 ENPP2 (0.64) ENPP2LPAR3LPAR1
SCHEMBL6371447 0.86 DNM1 (0.54) PRKCAPRKCEPRKCQPRKCDENPP2
SCHEMBL14754796 0.86 FABP3 (0.72) PRKCAPRKCEPRKCQPRKCDENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0726761-B1 MICROPARTICULAR PHARMACEUTICAL COMPOSITIONS IN MICELLAR FORM ISOMED INC (US) 2001-01-10 EP claimed
US-5858398-A MICROPARTICLES CONTAINING ACTIVE AGENT, MIXTURE OF PHOSPHOLIPIDS, MIXTURE OF NONIONIC SURFACTANTS, STEROL SUSPENDED IN FATTY ACID ISOMED INC. (US) 1999-01-12 US claimed
US-6602861-B1 Acylated phospholipid drugs RESEARCH CORPORATION TECHNOLOGIES, INC. 2003-08-05 US disclosed
EP-0726761-B1 MICROPARTICULAR PHARMACEUTICAL COMPOSITIONS IN MICELLAR FORM ISOMED INC (US) 2001-01-10 EP disclosed
US-5858398-A MICROPARTICLES CONTAINING ACTIVE AGENT, MIXTURE OF PHOSPHOLIPIDS, MIXTURE OF NONIONIC SURFACTANTS, STEROL SUSPENDED IN FATTY ACID ISOMED INC. (US) 1999-01-12 US disclosed
US-5846955-A Acylated phospholipid drugs RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1998-12-08 US disclosed
EP-0726761-A1 MICROPARTICULAR PHARMACEUTICAL COMPOSITIONS IN MICELLAR FORM ISOTECH MEDICAL, INC. (US) 1996-08-21 EP disclosed
WO-1995012385-A1 MICROPARTICULAR PHARMACEUTICAL COMPOSITIONS IN MICELLAR FORM ISOTECH MEDICAL, INC. (US) 1995-05-11 WO disclosed