SCHEMBL7204652

SCHEMBL7204652

CC/C=C\CCOC(=O)CC(C)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 2/20 0.42
NR1I2 O75469 1/20 0.42
PGR P06401 1/20 0.42
PTGS2 P35354 1/20 0.42
PDE4D Q08499 1/20 0.42
MGAM O43451 2/20 0.41
GAA P10253 2/20 0.41
SI P14410 2/20 0.41
MGAM2 Q2M2H8 2/20 0.41
FAAH O00519 2/20 0.41
ALDH1A1 P00352 7/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
OXER1 Q8TDS5 3/20 0.37
MAPT P10636 3/20 0.37
CYP19A1 P11511 2/20 0.37
RXRA P19793 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7204654 1.00 ADORA3 (0.42) ADORA3NR1I2PGRPTGS2PDE4D
SCHEMBL8084130 1.00 ADORA3 (0.42) ADORA3NR1I2PGRPTGS2PDE4D
SCHEMBL7694874 0.90 MGAM (0.46) ADORA3NR1I2PGRPTGS2PDE4D
SCHEMBL7694877 0.90 MGAM (0.46) ADORA3NR1I2PGRPTGS2PDE4D
SCHEMBL28335255 0.85 NR1I2 (0.45) ADORA3NR1I2PGRPTGS2PDE4D
SCHEMBL28141411 0.85 FAAH (0.53) FAAHALDH1A1MAPTLPAR2LPAR3
(Z)-Hex-3-En-1-Yl Acetate SCHEMBL28236821 0.85 NR1I2 (0.39) ADORA3NR1I2PGRPTGS2PDE4D
SCHEMBL22390233 0.83 ADORA3 (0.49) ADORA3NR1I2PGRPTGS2PDE4D
SCHEMBL649880 0.82 NAAA (0.47) ADORA3NR1I2PGRPTGS2PDE4D
SCHEMBL22832722 0.82 ADORA3 (0.55) ADORA3NR1I2PGRPTGS2PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4356894-A1 SUSTAINABLE PRODUCT WITH MALODORS Beiersdorf AG (DE) 2024-04-24 EP claimed
EP-0927238-B1 RINSE ADDED FABRIC SOFTENING COMPOSITIONS AND METHOD OF USE FOR THE DELIVERY OF FRAGRANCE DERIVATIVES PROCTER & GAMBLE (US) 2003-05-21 EP claimed
CN-1233283-A Rinse added fabric softening compositions and methods for delivering perfume derivatives PROCTER & GAMBLE (US) 1999-10-27 CN claimed
US-20240277012-A1 DUPLICATE BEVERAGE WANG JIE (US) 2024-08-22 US disclosed
EP-4356894-A1 SUSTAINABLE PRODUCT WITH MALODORS Beiersdorf AG (DE) 2024-04-24 EP disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 CN disclosed
EP-2852282-B1 METHODS FOR RENDERING MICELLAR COORDINATION COMPLEXES SAFE FOR THE TREATMENT OF PLANTS AND FORMULATIONS FOR SAME INNOVATION HAMMER LLC (US) 2019-04-24 EP disclosed
US-20150133298-A1 Methods For Rendering Micellar Coordination Complexes Safe For The Treatment Of Plants And Formulations For Same INNOVATION HAMMER, LLC 2015-05-14 US disclosed
EP-2852282-A2 METHODS FOR RENDERING MICELLAR COORDINATION COMPLEXES SAFE FOR THE TREATMENT OF PLANTS AND FORMULATIONS FOR SAME Innovation Hammer LLC (US) 2015-04-01 EP disclosed
WO-2013176731-A2 METHODS FOR RENDERING MICELLAR COORDINATION COMPLEXES SAFE FOR THE TREATMENT OF PLANTS AND FORMULATIONS FOR SAME NONOMURA ARTHUR M (US) 2013-11-28 WO disclosed
EP-0927238-B1 RINSE ADDED FABRIC SOFTENING COMPOSITIONS AND METHOD OF USE FOR THE DELIVERY OF FRAGRANCE DERIVATIVES PROCTER & GAMBLE (US) 2003-05-21 EP disclosed
US-6165953-A Dryer added fabric softening compositions and method of use for the delivery of fragrance derivatives THE PROCTER & GAMBLE COMPANY (US) 2000-12-26 US disclosed
US-6093691-A BETA-KETOESTER PROFRAGRANCES SUCH AS 3,7-DIMETHYL-1,6-OCTADIEN-3-YL 2-(BETA-NAPHTHY)-3-OXO-PROPIONATE, AND FABRIC SOFTENING INGREDIENTS SUCH AS CATIONIC FABRIC SOFTENERS, STABILIZERS THE PROCTER & GAMBLE COMPANY (US) 2000-07-25 US disclosed
CN-1233283-A Rinse added fabric softening compositions and methods for delivering perfume derivatives PROCTER & GAMBLE (US) 1999-10-27 CN disclosed
EP-0927238-A2 RINSE ADDED FABRIC SOFTENING COMPOSITIONS AND METHOD OF USE FOR THE DELIVERY OF FRAGRANCE DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1999-07-07 EP disclosed
WO-1998007811-A2 RINSE ADDED FABRIC SOFTENING COMPOSITIONS AND METHOD OF USE FOR THE DELIVERY OF FRAGRANCE DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1998-02-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 ADORA3 2392/4885NR1I2 3388/4885PGR 4769/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 ADORA3 2392/4885NR1I2 3388/4885PGR 4769/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 ADORA3 2392/4885NR1I2 3388/4885PGR 4769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.