Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 3/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7156759 | 0.83 | ADORA2A (0.39) | SLC16A3SLC16A1KMT2AMEN1MAPT | |
| SCHEMBL7204107 | 0.83 | MAPT (0.42) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL7166657 | 0.74 | TRPM8 (0.42) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL7205287 | 0.72 | MAPT (0.47) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL7205283 | 0.70 | KMT2A (0.56) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL4483001 | 0.69 | KMT2A (0.46) | SLC16A3SLC16A1KMT2AMEN1MAPT | |
| SCHEMBL4487336 | 0.67 | ALDH1A1 (0.47) | SLC16A3SLC16A1KMT2AMEN1MAPT | |
| SCHEMBL7191088 | 0.66 | NFE2L2 (0.38) | KMT2AMEN1MAPTALDH1A1EGFR | |
| SCHEMBL7191091 | 0.66 | NFE2L2 (0.38) | KMT2AMEN1MAPTALDH1A1EGFR | |
| SCHEMBL7156762 | 0.65 | KIF20A (0.43) | SLC16A3SLC16A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030109502-A1 | Novel compounds for modulating cell proliferation | HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP (CA) | 2003-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109502-A1 | Novel compounds for modulating cell proliferation | MKI67, CCNA1, CCNI | SLC16A3 3839/4885SLC16A1 2629/4885KMT2A 3487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.