Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203961 | 0.94 | ALDH1A1 (0.50) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL7206121 | 0.92 | ALOX15 (0.48) | ELANEALOX15 | |
| SCHEMBL7203048 | 0.88 | ALDH1A1 (0.50) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL6170675 | 0.87 | MAP2 (0.44) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL7203928 | 0.87 | ALDH1A1 (0.52) | ALDH1A1CYP1A2HPGDELANEPTGS2 | |
| SCHEMBL7206948 | 0.86 | KDM4E (0.48) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL7205567 | 0.86 | ALDH1A1 (0.42) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL7202561 | 0.85 | ALOX15 (0.50) | ALOX15 | |
| SCHEMBL7202043 | 0.84 | MDM2 (0.48) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL7205778 | 0.82 | ALOX15 (0.47) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608070-B1 | Useful for treatment of medical condition in which prostaglandins are implicated as pathogens | NAKAO KAZUNARI (JP) | 2003-08-19 | — | — | US | disclosed |