Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.48 |
| ▸ | TUBB | P07437 | 3/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172246 | 0.89 | KMT2A (0.45) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL7206101 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL7206121 | 0.80 | ALOX15 (0.48) | ELANE | |
| SCHEMBL7203961 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL8140740 | 0.78 | MEN1 (0.49) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL6168282 | 0.78 | PTGS2 (0.68) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL6168601 | 0.78 | KMT2A (0.48) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL27569322 | 0.78 | KMT2A (0.46) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL7205567 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL7206948 | 0.77 | KDM4E (0.48) | ALDH1A1KDM4EHPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608070-B1 | Useful for treatment of medical condition in which prostaglandins are implicated as pathogens | NAKAO KAZUNARI (JP) | 2003-08-19 | — | — | US | disclosed |