SCHEMBL7206885

SCHEMBL7206885

COCC(COC(=O)O)OC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 5/20 0.37
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
PRKCE Q02156 1/20 0.33
PRKCQ Q04759 1/20 0.33
PRKCD Q05655 1/20 0.33
LPAR6 P43657 1/20 0.32
LPAR1 Q92633 1/20 0.32
LPAR4 Q99677 1/20 0.32
LPAR5 Q9H1C0 1/20 0.32
LPAR2 Q9HBW0 1/20 0.32
LPAR3 Q9UBY5 1/20 0.32
SERPINE1 P05121 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1030922 0.89 SERPINE1 (0.36) PRKCAALDH1A1LMNASERPINE1PTPN1
SCHEMBL20955974 0.86 ALDH1A1 (0.31) PRKCAALDH1A1
SCHEMBL12311562 0.84 ENPP2 (0.37) PRKCAALDH1A1LPAR6LPAR1LPAR4
SCHEMBL2266760 0.82 PRKCA (0.48) PRKCAPRKCEPRKCQPRKCD
SCHEMBL30585906 0.82 PRKCA (0.48) PRKCAPRKCEPRKCQPRKCD
SCHEMBL7534968 0.81 PRKCA (0.36) PRKCAALDH1A1LMNAPRKCEPRKCQ
SCHEMBL5484842 0.80 MEN1 (0.35) PRKCAALDH1A1PRKCDLPAR6LPAR1
SCHEMBL162345 0.80 ALDH1A1 (0.36) PRKCAALDH1A1LMNAPRKCEPRKCQ
SCHEMBL1729808 0.79 PRKCA (0.32) PRKCAALDH1A1LMNASERPINE1
SCHEMBL3393123 0.79 PRKCA (0.32) PRKCAALDH1A1LMNASERPINE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4002676-A SEQUESTERING AGENT HENKEL & CIE G.M.B.H. (DT) 1977-01-11 US claimed
US-11197818-B2 Aqueous emulsions of carbamato-functionalized organopolysiloxanes WACKER CHEMIE AG (DE) 2021-12-14 US disclosed
CN-109152723-B Aqueous emulsions of carbamate-functional organopolysiloxanes 瓦克化学股份公司 2021-11-09 CN disclosed
CN-108779415-B Composition containing carbamate-functional organopolysiloxane and cationic surfactant 瓦克化学股份公司 2021-11-05 CN disclosed
US-10675230-B2 Compositions comprising carbamate functionalized organopolysiloxanes and cationic surfactants WACKER CHEMIE AG (DE) 2020-06-09 US disclosed
US-20190133919-A1 AQUEOUS EMULSIONS OF CARBAMATO-FUNCTIONALIZED ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2019-05-09 US disclosed
US-20190133906-A1 COMPOSITIONS COMPRISING CARBAMATE FUNCTIONALIZED ORGANOPOLYSILOXANES AND CATIONIC SURFACTANTS WACKER CHEMIE AG (DE) 2019-05-09 US disclosed
EP-0893428-B1 A process for preparing dialkyl carbonates NIPPON CATALYTIC CHEM IND (JP) 2003-01-22 EP disclosed
EP-0599287-B1 A process for preparing dialkyl carbonates NIPPON CATALYTIC CHEM IND (JP) 1999-04-07 EP disclosed
EP-0893428-A1 A process for preparing dialkyl carbonates NIPPON SHOKUBAI CO., LTD. (JP) 1999-01-27 EP disclosed
US-5430170-A Esterification of alkalene carbonate with an alcohol in presence of rare earth catalyst NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-04 US disclosed
EP-0599287-A1 A process for preparing dialkyl carbonates NIPPON SHOKUBAI CO., LTD. (JP) 1994-06-01 EP disclosed
US-4332729-A CATALYZED CYCLIZATION THE DOW CHEMICAL COMPANY (US) 1982-06-01 US disclosed
US-4331604-A Preparation of cyclic carbonates THE DOW CHEMICAL COMPANY (US) 1982-05-25 US disclosed
US-4002676-A SEQUESTERING AGENT HENKEL & CIE G.M.B.H. (DT) 1977-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10675230-B2 Compositions comprising carbamate functionalized organopolysiloxanes and cationic surfactants C9, CUTA, NISCH PRKCA 4315/4885ALDH1A1 3674/4885LMNA 1927/4885
US-11197818-B2 Aqueous emulsions of carbamato-functionalized organopolysiloxanes HMBS, CBLB, LIPA PRKCA 4324/4885ALDH1A1 2689/4885LMNA 1089/4885
US-20190133906-A1 COMPOSITIONS COMPRISING CARBAMATE FUNCTIONALIZED ORGANOPOLYSILOXANES AND CATIONIC SURFACTANTS C9, CUTA, NISCH PRKCA 4315/4885ALDH1A1 3674/4885LMNA 1927/4885
US-20190133919-A1 AQUEOUS EMULSIONS OF CARBAMATO-FUNCTIONALIZED ORGANOPOLYSILOXANES HMBS, CBLB, LIPA PRKCA 4324/4885ALDH1A1 2689/4885LMNA 1089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.