Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206345 | 0.88 | GABRA1 (0.41) | SOAT2MYCSOAT1MAP2K3GABRA1 | |
| SCHEMBL7109320 | 0.87 | FABP3 (0.35) | SOAT2MYCSOAT1MAP2K3FABP3 | |
| SCHEMBL7206867 | 0.81 | SRD5A2 (0.38) | SOAT2MYCSOAT1MAP2K3FABP3 | |
| SCHEMBL7206905 | 0.80 | NPC1 (0.30) | — | |
| SCHEMBL7207657 | 0.80 | FABP3 (0.44) | SOAT2MYCSOAT1MAP2K3FABP3 | |
| SCHEMBL7212856 | 0.77 | AKR1B1 (0.41) | — | |
| SCHEMBL7108812 | 0.76 | FABP3 (0.36) | FABP3FABP4FABP5GABRA1GABRB2 | |
| SCHEMBL7206928 | 0.76 | FABP3 (0.41) | SOAT2MYCSOAT1MAP2K3FABP3 | |
| SCHEMBL7207810 | 0.76 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL7104860 | 0.75 | FABP3 (0.36) | FABP3FABP4FABP5GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841913-B1 | USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | EP | claimed |