Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206345 | 0.81 | GABRA1 (0.41) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7206924 | 0.80 | SOAT2 (0.39) | — | |
| SCHEMBL7212856 | 0.78 | AKR1B1 (0.41) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7207810 | 0.77 | SMN1; SMN2 (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL7206388 | 0.76 | TSHR (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7206911 | 0.76 | HPGD (0.32) | ALDH1A1 | |
| SCHEMBL7212819 | 0.70 | TTR (0.53) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7109320 | 0.70 | FABP3 (0.35) | — | |
| SCHEMBL7206377 | 0.69 | LMNA (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7206942 | 0.69 | POLQ (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841913-B1 | USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | EP | claimed |