Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 5/20 | 1.00 |
| ▸ | PARP1 | P09874 | 4/20 | 1.00 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.78 |
| ▸ | HPGD | P15428 | 4/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.78 |
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | TP53 | P04637 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | GLA | P06280 | 1/20 | 0.78 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | BCHE | P06276 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | ACHE | P22303 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29677954 | 1.00 | TNKS (1.00) | TNKSPARP1TNKS2CYP3A4HPGD | |
| SCHEMBL29384142 | 1.00 | TNKS (1.00) | TNKSPARP1TNKS2CYP3A4HPGD | |
| Flavone SCHEMBL27534477 | 0.89 | TNKS (0.85) | TNKSPARP1TNKS2CYP3A4HPGD | |
| SCHEMBL4277649 | 0.88 | MAPT (1.00) | TNKSPARP1TNKS2CYP3A4HPGD | |
| SCHEMBL3135989 | 0.88 | CYP3A4 (1.00) | TNKSPARP1TNKS2CYP3A4HPGD | |
| SCHEMBL31675776 | 0.88 | CYP3A4 (1.00) | TNKSPARP1TNKS2CYP3A4HPGD | |
| SCHEMBL1483977 | 0.87 | TNKS (0.77) | TNKSPARP1TNKS2CYP3A4HPGD | |
| SCHEMBL29773081 | 0.84 | TNKS (1.00) | TNKSPARP1TNKS2CYP3A4HPGD | |
| SCHEMBL127446 | 0.84 | TNKS (1.00) | TNKSPARP1TNKS2CYP3A4HPGD | |
| Flavone SCHEMBL15676601 | 0.83 | TNKS (1.00) | TNKSPARP1TNKS2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230119060-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING, AS ACTIVE INGREDIENT, COMPLEX OF BIGUANIDE-BASED COMPOUND AND FLAVONE, HYDROXYFLAVONE, FLAVANONE, FLAVONE DERIVATIVE, HYDROXYFLAVONE DERIVATIVE, OR FLAVANONE DERIVATIVE | MEDIENCE CO., LTD. (KR) | 2023-04-20 | — | — | US | claimed |
| US-20220249431-A1 | ANTIMYCOTIC | Karl-Franzens-Universität Graz (AT) | 2022-08-11 | — | — | US | claimed |
| EP-4003522-A1 | ANTIMYCOTIC | Karl-Franzens-Universität Graz (AT) | 2022-06-01 | — | — | EP | claimed |
| WO-2021013931-A1 | ANTIMYCOTIC | Karl-Franzens-Universität Graz (AT) | 2021-01-28 | — | — | WO | claimed |
| EP-3769815-A1 | ANTIMYCOTIC | Karl-Franzens-Universität Graz (AT) | 2021-01-27 | — | — | EP | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| US-20040086983-A1 | Method for producing a heterocyclic compound and an aromatic carboxylic acid having one or more hydroxyl groups, and modified aromatic ring dioxygenase | MARINE BIOTHECHNOLOGY INSTITUTE., LTD. (JP) | 2004-05-06 | — | — | US | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| US-20250263774-A1 | DISCOVERING NEW XENOBIOTIC SUBSTRATES OF AN UDP-GLYCOSYLTRANSFERASE WITH A HIGH-THROUGHPUT METHOD | UNIV NORTH TEXAS (US) | 2025-08-21 | — | — | US | disclosed |
| CN-118001403-A | Method for preparing phosphoric acid nano-drug based on competitive coordination and multifunctional nano-drug | 吉林大学 | 2024-05-10 | — | — | CN | disclosed |
| US-11786503-B2 | Pharmaceutical compositions and methods for countering chemotherapy induced cardiotoxicity | AURANSA INC. (US) | 2023-10-17 | — | — | US | disclosed |
| CN-114014905-B | Glycyrrhetinic acid derivative targeting PPARgamma as well as preparation method and application thereof | 浙江科技学院 | 2023-07-21 | — | — | CN | disclosed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| US-20020128494-A1 | N-Disubstituted carbamoyloxy flavones | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2002-09-12 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128494-A1 | N-Disubstituted carbamoyloxy flavones | CBR3, FOS, CBR1 | TNKS 4063/4885PARP1 3627/4885TNKS2 4036/4885 |
| US-20220249431-A1 | ANTIMYCOTIC | ETF1, FOXM1, RIF1 | TNKS 4403/4885PARP1 3190/4885TNKS2 4431/4885 |
| US-11786503-B2 | Pharmaceutical compositions and methods for countering chemotherapy induced cardiotoxicity | RDX, TNNT2, CHLSN | TNKS 2925/4885PARP1 953/4885TNKS2 2746/4885 |
| US-20230119060-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING, AS ACTIVE INGREDIENT, COMPLEX OF BIGUANIDE-BASED COMPOUND AND FLAVONE, HYDROXYFLAVONE, FLAVANONE, FLAVONE DERIVATIVE, HYDROXYFLAVONE DERIVATIVE, OR FLAVANONE DERIVATIVE | SLC5A2, SLC5A1, SLC5A6 | TNKS 4575/4885PARP1 4024/4885TNKS2 4500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.