Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 12/20 | 0.36 |
| ▸ | TK1 | P04183 | 6/20 | 0.33 |
| ▸ | PLD2 | O14939 | 1/20 | 0.32 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024558 | 0.90 | TK2 (0.36) | TK2TK1 | |
| SCHEMBL6831414 | 0.78 | TK1 (0.38) | TK2TK1 | |
| SCHEMBL6831419 | 0.78 | TK1 (0.38) | TK2TK1 | |
| SCHEMBL7207621 | 0.76 | RNASE1 (0.37) | TK2TK1PLD2PLD1 | |
| SCHEMBL6831448 | 0.75 | TK2 (0.36) | TK2TK1PLD2PLD1 | |
| SCHEMBL7899020 | 0.72 | TK2 (0.41) | TK2TK1 | |
| SCHEMBL6836547 | 0.71 | MAPT (0.36) | — | |
| SCHEMBL26653633 | 0.69 | TK1 (0.34) | TK2TK1 | |
| SCHEMBL7207527 | 0.69 | RNASE1 (0.34) | TK2TK1 | |
| SCHEMBL8932076 | 0.68 | TYMP (0.39) | TK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610837-B1 | Preparation of an oligonucleotide compound of given formula by reacting with given compounds, followed by oxidation or sulfurization | ISIS PHARMACEUTICALS, INC. | 2003-08-26 | — | — | US | disclosed |