Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108812 | 0.82 | FABP3 (0.36) | FABP3FABP4 | |
| SCHEMBL7104860 | 0.81 | FABP3 (0.36) | FABP3FABP4 | |
| SCHEMBL7207646 | 0.79 | ALDH1A1 (0.38) | FABP3FABP4ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL8495041 | 0.72 | FABP3 (0.49) | FABP3FABP4ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL7206855 | 0.72 | SOAT2 (0.36) | FABP3FABP4ALDH1A1CYP3A4RARG | |
| SCHEMBL7206924 | 0.72 | SOAT2 (0.39) | FABP3FABP4 | |
| SCHEMBL7206867 | 0.71 | SRD5A2 (0.38) | FABP3FABP4RARGRXRAPPARG | |
| SCHEMBL7109320 | 0.70 | FABP3 (0.35) | FABP3FABP4 | |
| SCHEMBL7105194 | 0.70 | FABP3 (0.35) | FABP3FABP4 | |
| SCHEMBL7207547 | 0.66 | L3MBTL1 (0.43) | ALDH1A1HSD17B10RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841913-B1 | USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | EP | claimed |