Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211246 | 0.84 | LMNA (0.47) | KMT2AMEN1SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL7207547 | 0.81 | L3MBTL1 (0.43) | CHRM2CHRM4CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL7211283 | 0.81 | PTGS2 (0.40) | KMT2AMEN1SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL7207787 | 0.77 | CHRM2 (0.43) | CHRM2CHRM4CHRM1CHRM3CYP2D6 | |
| SCHEMBL7206377 | 0.76 | LMNA (0.37) | SMN1; SMN2LMNAALDH1A1HPGDPOLB | |
| SCHEMBL7206890 | 0.72 | CHRM3 (0.44) | CHRM2CHRM1CHRM3CYP2D6KMT2A | |
| SCHEMBL7211946 | 0.72 | CHRM3 (0.45) | CHRM2CHRM1CHRM3CYP2D6KMT2A | |
| SCHEMBL23872457 | 0.70 | CYP2D6 (0.61) | CHRM2CHRM4CHRM1CHRM3CYP2D6 | |
| SCHEMBL4921518 | 0.70 | CYP2D6 (0.61) | CHRM2CHRM4CHRM1CHRM3CYP2D6 | |
| SCHEMBL499471 | 0.70 | CYP2D6 (0.61) | CHRM2CHRM4CHRM1CHRM3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841913-B1 | USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | EP | claimed |