Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2287889 | 0.77 | GAA (0.48) | GAAALDH1A1KDM4EMAPTHTT | |
| SCHEMBL8376596 | 0.75 | DRD2 (0.39) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL2292533 | 0.73 | TSPO (0.33) | GAAMEN1KMT2ATSPOALPL | |
| SCHEMBL2292527 | 0.72 | ALOX5 (0.48) | GAAALDH1A1KDM4EMEN1KMT2A | |
| Sulfuric Acid SCHEMBL29282027 | 0.71 | GAA (0.36) | GAAALDH1A1MAPTTP53MEN1 | |
| SCHEMBL10102354 | 0.71 | GAA (0.40) | GAAALDH1A1KDM4EMAPTTP53 | |
| SCHEMBL2291992 | 0.70 | AKR1B1 (0.39) | GAAKDM4EMEN1KMT2ATSPO | |
| SCHEMBL2291776 | 0.70 | MAPK1 (0.41) | GAAALDH1A1KDM4EMAPTHTT | |
| Sulfuric Acid SCHEMBL10339576 | 0.69 | ALDH1A1 (0.38) | GAAALDH1A1KDM4EMAPTMEN1 | |
| Sulfuric Acid SCHEMBL31514469 | 0.69 | ALDH1A1 (0.38) | GAAALDH1A1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030031676-A1 | Conjugate compounds for treating atheroma and other diseases | PHARMACYCLICS, INC. | 2003-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030031676-A1 | Conjugate compounds for treating atheroma and other diseases | NQO1, AKR7A2, CYP46A1 | GAA 277/4885ALDH1A1 176/4885KDM4E 4484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.