Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.70 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | USP8 | P40818 | 1/20 | 0.61 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.51 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.49 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7631719 | 0.89 | SLC20A2 (0.86) | SLC20A2SLC20A1USP2USP8AVPR2 | |
| SCHEMBL7533744 | 0.84 | SLC20A2 (0.58) | SLC20A2SLC20A1USP2USP8AVPR2 | |
| SCHEMBL7128814 | 0.82 | SLC20A2 (1.00) | SLC20A2SLC20A1USP2USP8AVPR2 | |
| SCHEMBL30927042 | 0.82 | MEN1 (0.64) | SLC20A2SLC20A1USP2USP8AVPR2 | |
| SCHEMBL27179805 | 0.82 | MEN1 (0.64) | SLC20A2SLC20A1USP2USP8AVPR2 | |
| SCHEMBL28454669 | 0.79 | MEN1 (0.64) | SLC20A2SLC20A1AVPR2GPR27RXFP1 | |
| SCHEMBL7209352 | 0.79 | AVPR2 (0.59) | AVPR2GPR27LMNAMAPT | |
| SCHEMBL7126685 | 0.77 | SLC20A2 (0.83) | SLC20A2SLC20A1USP2USP8AVPR2 | |
| SCHEMBL7572438 | 0.76 | SLC20A2 (0.63) | SLC20A2SLC20A1USP2USP8LMNA | |
| SCHEMBL12201483 | 0.76 | SLC20A2 (0.72) | SLC20A2SLC20A1USP2USP8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187531-A4 | MACROPHAGE SCAVENGER RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-05-28 | — | — | EP | claimed |
| US-6458845-B1 | METHOD OF ANTAGONIZING A MACROPHAGE SCAVENGER RECEPTOR COMPRISING ADMINISTERING TO A SUBJECT IN NEED OF TREATMENT AN EFFECTIVE AMOUNT OF AN N-PHENYL-2-(3-TRIFLUOROMETHYLPHENYLSULFONAMIDO)BENZAMIDE, A | SMITHKLINE BEECHAM CORPORATION | 2002-10-01 | — | — | US | claimed |
| EP-1187531-A1 | MACROPHAGE SCAVENGER RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2002-03-20 | — | — | EP | claimed |
| WO-2001098264-A1 | MACROPHAGE SCAVENGER RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-27 | — | — | WO | claimed |
| WO-2000078145-A1 | MACROPHAGE SCAVENGER RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-28 | — | — | WO | claimed |