Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.58 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.58 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.45 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | USP8 | P40818 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537216 | 0.87 | ALDH1A1 (0.58) | POLBAVPR2GPR27SMN1; SMN2ALDH1A1 | |
| SCHEMBL7530790 | 0.85 | SLC20A2 (0.65) | SLC20A2SLC20A1CCR2POLBAVPR2 | |
| SCHEMBL7537253 | 0.85 | IDH2 (0.54) | SLC20A2SLC20A1CCR2POLBNPC1 | |
| SCHEMBL7532778 | 0.85 | SLC20A2 (0.54) | SLC20A2SLC20A1CCR2POLBSMN1; SMN2 | |
| SCHEMBL7208743 | 0.84 | SLC20A2 (0.70) | SLC20A2SLC20A1AVPR2GPR27USP2 | |
| SCHEMBL7538011 | 0.84 | LMNA (0.55) | POLBAVPR2GPR27SMN1; SMN2ALDH1A1 | |
| SCHEMBL7562743 | 0.84 | ACLY (0.52) | SLC20A2SLC20A1CCR2AVPR2GPR27 | |
| SCHEMBL7538052 | 0.80 | SMN1; SMN2 (0.56) | POLBSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL7532056 | 0.80 | SMN1; SMN2 (0.47) | POLBSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL1200684 | 0.79 | PARP14 (0.62) | SLC20A2SLC20A1CCR2USP2USP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |