Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 4/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6846525 | 0.97 | ACHE (0.39) | ACHEENPP2APOBEC3AAPOBEC3GTBXAS1 | |
| Hydrochloric Acid SCHEMBL8222907 | 0.85 | ACHE (0.45) | ACHEENPP2APOBEC3AAPOBEC3GTBXAS1 | |
| Hydrochloric Acid SCHEMBL8695365 | 0.85 | ACHE (0.45) | ACHEENPP2APOBEC3AAPOBEC3GTBXAS1 | |
| Hydrochloric Acid SCHEMBL324011 | 0.85 | ACHE (0.52) | ACHEENPP2TBXAS1BBOX1MAPT | |
| Hydrochloric Acid SCHEMBL2936558 | 0.81 | ACHE (0.52) | ACHEENPP2APOBEC3AAPOBEC3GTBXAS1 | |
| Methacrylic Acid SCHEMBL6561454 | 0.80 | ACHE (0.52) | ACHEENPP2APOBEC3AAPOBEC3GTBXAS1 | |
| Hydrochloric Acid SCHEMBL9497105 | 0.78 | APEX1 (0.48) | ACHEENPP2APOBEC3AAPOBEC3GTBXAS1 | |
| SCHEMBL661125 | 0.78 | ACHE (0.41) | ACHEENPP2APOBEC3AAPOBEC3GBBOX1 | |
| Hydrochloric Acid SCHEMBL1703796 | 0.76 | ACHE (0.45) | ACHEENPP2APOBEC3AAPOBEC3GTBXAS1 | |
| Methacrylic Acid SCHEMBL159154 | 0.73 | ACHE (0.48) | ACHEENPP2APOBEC3AAPOBEC3GBBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030099710-A1 | Granule modulating hydrogel system | ANDRX CORPORATION | 2003-05-29 | — | — | US | disclosed |
| US-20010001658-A1 | Granule modulating hydrogel system | ANDRX PHARMACEUTICALS, LLC | 2001-05-24 | — | — | US | disclosed |
| WO-2000004879-A1 | GRANULE MODULATING HYDROGEL SYSTEM | ANDRIX PHARMACEUTICALS, INC. (US) | 2000-02-03 | — | — | WO | disclosed |