Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949941 | 0.98 | EPHX2 (0.45) | EPHX2ALDH1A1HPGDGLAL3MBTL1 | |
| SCHEMBL8655174 | 0.83 | GBA1 (0.47) | ALDH1A1HPGDGLAL3MBTL1LMNA | |
| SCHEMBL7368098 | 0.82 | LMNA (0.49) | EPHX2ALDH1A1HPGDGLAL3MBTL1 | |
| SCHEMBL9342644 | 0.75 | AKR1B1 (0.46) | EPHX2ALDH1A1HPGDLMNAUSP2 | |
| SCHEMBL163232 | 0.74 | EPHX2 (0.59) | EPHX2ALDH1A1HPGDGLAL3MBTL1 | |
| SCHEMBL5400951 | 0.73 | CES2 (0.41) | ALDH1A1L3MBTL1 | |
| SCHEMBL800064 | 0.72 | EPHX2 (0.56) | EPHX2ALDH1A1HPGDGLAL3MBTL1 | |
| SCHEMBL8376363 | 0.71 | EPHX2 (0.47) | EPHX2ALDH1A1HPGDGLAL3MBTL1 | |
| SCHEMBL11586847 | 0.71 | EPHX2 (0.56) | EPHX2ALDH1A1HPGDGLAL3MBTL1 | |
| Phenylacetic Acid SCHEMBL10408649 | 0.71 | AKR1B1 (0.61) | EPHX2ALDH1A1HPGDL3MBTL1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613880-B2 | Autoimmune diseases; inflammatory conditions; competitive binding with Human Leukocyte Antigen displacing disease-inducing endogenous peptides | PHARMACIA CORPORATION | 2003-09-02 | — | — | US | claimed |