SCHEMBL7209892

SCHEMBL7209892

C=Cc1ccc(OC(C)(OCC)c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.38
ALDH1A1 P00352 4/20 0.37
TSHR P16473 1/20 0.37
CHRNA7 P36544 4/20 0.37
CHRNB4 P30926 3/20 0.37
CHRNA3 P32297 3/20 0.37
CHRNB2 P17787 2/20 0.37
CHRNA4 P43681 2/20 0.37
PPARA Q07869 4/20 0.33
PPARG P37231 3/20 0.33
KMT2A Q03164 3/20 0.33
MAPT P10636 3/20 0.33
MEN1 O00255 2/20 0.33
KDM4E B2RXH2 2/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6699133 0.78 CHRNB2 (0.42) RELAALDH1A1TSHRCHRNA7CHRNB4
SCHEMBL5352713 0.78 MAPK1 (0.45) RELAALDH1A1TSHRCHRNA7CHRNB4
SCHEMBL27834859 0.77 CYP2C19 (0.39) ALDH1A1TSHRPPARGKMT2AMAPT
SCHEMBL6877807 0.77 FBP1 (0.34) ALDH1A1
SCHEMBL5198302 0.76 ALDH1A1 (0.43) RELAALDH1A1TSHRCHRNA7CHRNB4
SCHEMBL6694134 0.75 CHRNB2 (0.41) RELAALDH1A1TSHRCHRNA7CHRNB4
SCHEMBL6694490 0.75 CHRNB2 (0.41) RELAALDH1A1TSHRCHRNA7CHRNB4
SCHEMBL1802466 0.75 MAPK1 (0.46) ALDH1A1CYP2D6ALOX15TAAR1KIF11
SCHEMBL5199756 0.74 ALDH1A1 (0.48) RELAALDH1A1TSHRCHRNA7CHRNB4
Styrene SCHEMBL4582900 0.74 ALDH1A1 (0.54) RELAALDH1A1TSHRCHRNA7CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1344109-A2 ONIUM SALTS AND THE USE THEROF AS LATENT ACIDS Ciba SC Holding AG (CH) 2003-09-17 EP disclosed
WO-2002046507-A2 ONIUM SALTS AND THE USE THEROF AS LATENT ACIDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-06-13 WO disclosed