SCHEMBL7210271

SCHEMBL7210271

CC1(c2ccccc2)CCC[Si](C)(C)O1.C[Si]1(C)CCCCO1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3263252 0.91 HSD11B1 (0.36) HSD11B1ALDH1A1CYP1A2
SCHEMBL17512349 0.75 HSD11B1 (0.35) HSD11B1ALDH1A1CYP1A2TSHR
SCHEMBL6531179 0.74 HSD11B1 (0.34) HSD11B1ALDH1A1CYP1A2TSHR
SCHEMBL8405436 0.74 HSD11B1 (0.34) HSD11B1ALDH1A1CYP1A2
Biphenyl SCHEMBL1534225 0.73 ALDH1A1 (0.38) ALDH1A1CYP1A2
SCHEMBL11277242 0.73 HSD11B1 (0.36) HSD11B1ALDH1A1CYP1A2
SCHEMBL182247 0.73 OPRM1 (0.35) ALDH1A1
Toluene SCHEMBL28899269 0.72 LMNA (0.44) TSHR
Ammonia Solution, Strong SCHEMBL7597471 0.71 OPRM1 (0.34) ALDH1A1
SCHEMBL3365469 0.71 OPRM1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6602495-B2 For conditioning and bodifying the hair UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. 2003-08-05 US disclosed
US-20020090350-A1 Hair care compositions and method for depositing swollen polymer particles onto hair UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-07-11 US disclosed
US-6355233-B1 POLYSILOXANE CROSSLINKED WITH ALIPHATIC DIENE UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-03-12 US disclosed