Glutarate

Glutarate

SCHEMBL721029

N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO.O=C(O)CCCC(=O)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.47
SLCO1B1 Q9Y6L6 1/20 0.47
PDE4A P27815 1/20 0.41
PAX8 Q06710 1/20 0.41
LMNA P02545 4/20 0.39
SLC22A6 Q4U2R8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
AKR1B1 P15121 1/20 0.34
CAMK2A Q9UQM7 1/20 0.34
ENPEP Q07075 3/20 0.34
GABRR3 A8MPY1 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
HDAC3 O15379 1/20 0.33
GABBR2 O75899 1/20 0.33
CYP1A2 P05177 1/20 0.33
THRB P10828 1/20 0.33
GABRA1 P14867 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutarate SCHEMBL17748589 1.00 USP2 (0.47) USP2SLCO1B1PDE4APAX8LMNA
Adipic Acid SCHEMBL17748607 0.97 USP2 (0.47) USP2SLCO1B1PDE4APAX8LMNA
Azelaic Acid SCHEMBL5981826 0.95 USP2 (0.46) USP2SLCO1B1PDE4APAX8LMNA
Succinic Acid SCHEMBL722957 0.93 USP2 (0.50) USP2SLCO1B1PDE4APAX8LMNA
Succinic Acid SCHEMBL17748517 0.93 USP2 (0.50) USP2SLCO1B1PDE4APAX8LMNA
Palmitic Acid SCHEMBL2775373 0.88 GPR84 (0.49) USP2PDE4ALMNASLC22A6TDP1
Bicarbonate SCHEMBL20888 0.87 USP2 (0.55) USP2SLCO1B1PDE4APAX8LMNA
Malonic Acid SCHEMBL17748563 0.86 USP2 (0.50) USP2SLCO1B1PDE4APAX8LMNA
Glycine SCHEMBL2842691 0.86 USP2 (0.50) USP2SLCO1B1PDE4APAX8LMNA
Malonic Acid SCHEMBL5866696 0.86 USP2 (0.50) USP2SLCO1B1PDE4APAX8LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9585988-B2 Anchorage devices comprising an active pharmaceutical ingredient TYRX, INC. (US) 2017-03-07 US claimed
US-12447242-B2 Hemostatic devices and methods of use MEDTRONIC, INC. (US) 2025-10-21 US disclosed
EP-3452124-B1 HEMOSTATIC DEVICES AND METHODS OF USE MEDTRONIC INC (US) 2025-10-08 EP disclosed
EP-3452123-B1 HEMOSTATIC DEVICES AND METHODS OF USE MEDTRONIC INC (US) 2025-09-24 EP disclosed
EP-3452126-B1 HEMOSTATIC DEVICES AND METHODS OF USE MEDTRONIC INC (US) 2025-08-27 EP disclosed
US-20250262358-A1 SURGICAL SYSTEM AND METHODS OF USE MEDTRONIC INC (US) 2025-08-21 US disclosed
EP-3452125-B1 CUSTOMIZABLE ANCHORAGE DEVICES AND METHODS OF USE MEDTRONIC INC (US) 2025-07-16 EP disclosed
US-20250152332-A1 SURGICAL SYSTEM AND METHODS OF USE MEDTRONIC, INC. 2025-05-15 US disclosed
US-12168086-B2 Hemostatic devices and methods of use MEDTRONIC, INC (US) 2024-12-17 US disclosed
US-12168085-B2 Surgical system and methods of use MEDTRONIC, INC (US) 2024-12-17 US disclosed
EP-2079387-A1 MESH POUCHES FOR IMPLANTABLE MEDICAL DEVICES TYRX PHARMA INC. (US) 2009-07-22 EP disclosed
US-20090088548-A1 Resorbable Phenolic Polymers TYRX PHARMA, INC. (US) 2009-04-02 US disclosed
US-20090018559-A1 Temporarily Stiffened Mesh Prostheses TYRX PHARMA, INC. (US) 2009-01-15 US disclosed
WO-2008136856-A2 RESORBABLE POUCHES FOR IMPLANTABLE MEDICAL DEVICES TYRX PHARMA, INC. (US) 2008-11-13 WO disclosed
WO-2008127411-A1 MESH POUCHES FOR IMPLANTABLE MEDICAL DEVICES TYRX PHARMA, INC. (US) 2008-10-23 WO disclosed
WO-2008121816-A2 BIODEGRADABLE, POLYMER COVERINGS FOR BREAST IMPLANTS TYRX PHARMA, INC. (US) 2008-10-09 WO disclosed
US-20080241212-A1 Tyrosine-derived aromatic polyester sheet, film or mat of nanofibers optionally including anesthetics, antiinflammatories, microbiocides, leukotriene inhibitors, or antiscarring, antifibrotic, or antineoplastic agents, and that resists capsular contracture and adherence to the implant TYRX PHARMA, INC. (US) 2008-10-02 US disclosed
US-20080132922-A1 Mesh Pouches for Implantable Medical Devices TYRX PHARMA, INC. (US) 2008-06-05 US disclosed
US-20080128315-A1 Biodegradable polylactic acid polymer pouches for pacemaker, defibrillator, pulse generator cardiac rhythm mamagent devices; antimicrobial agents, anesthetics, anti-inflammatory agents, anti-scarring drugs in polymer matrix; barrier to microbial colonization of medical device during surgical implantation TYRX PHARMA, INC. (US) 2008-06-05 US disclosed
US-20070198040-A1 Temporarily Stiffened Mesh Prostheses TYRX PHARMA INC. (US) 2007-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090088548-A1 Resorbable Phenolic Polymers PAH, PUF60, MKI67 USP2 2276/4885SLCO1B1 1907/4885PDE4A 3644/4885
US-12168086-B2 Hemostatic devices and methods of use PLAT, HABP2, F2 USP2 725/4885SLCO1B1 4876/4885PDE4A 2991/4885
US-12168085-B2 Surgical system and methods of use FGB, F2, COL14A1 USP2 1094/4885SLCO1B1 4844/4885PDE4A 2854/4885
US-12447242-B2 Hemostatic devices and methods of use HABP2, PLAT, F2 USP2 506/4885SLCO1B1 4878/4885PDE4A 2974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.