Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 5/20 | 0.61 |
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA9 | Q16790 | 4/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210775 | 0.86 | PTGS2 (0.64) | PTGS2PTGS1ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL7210290 | 0.86 | PTGS2 (0.70) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL7212148 | 0.84 | PTGS2 (0.76) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL7215299 | 0.83 | PTGS2 (0.70) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL7212078 | 0.82 | PTGS2 (0.58) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL7215905 | 0.79 | PTGS2 (0.58) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL8506129 | 0.78 | CA2 (0.50) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL7210655 | 0.78 | PTGS2 (0.76) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL10059589 | 0.77 | CA2 (0.65) | PTGS2CA2CA1CA9CA12 | |
| SCHEMBL5311727 | 0.77 | PTGS2 (0.74) | PTGS2PTGS1CA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1369415-A1 | Substituted pyrrolyl compounds for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2003-12-10 | — | — | EP | claimed |
| EP-1369415-A1 | Substituted pyrrolyl compounds for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2003-12-10 | — | — | EP | disclosed |