Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.37 |
| ▸ | TSHR | P16473 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209905 | 0.92 | ATM (0.40) | ATMALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL7215055 | 0.85 | ATM (0.39) | ATMALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL22808138 | 0.72 | ATM (0.42) | ATMALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL30801699 | 0.71 | CTSL (0.49) | ATMALDH1A1CTSBCTSLCTSS | |
| SCHEMBL7209268 | 0.71 | CTSS (0.41) | ATMALDH1A1CYP3A4TSHRCTSB | |
| SCHEMBL8815770 | 0.71 | ALDH1A1 (0.56) | ALDH1A1CYP3A4LMNAKMT2AMAPK1 | |
| SCHEMBL23042877 | 0.70 | PDE1B (0.33) | ALDH1A1CYP3A4TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL10504264 | 0.69 | CYP3A4 (0.45) | ATMALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL8857439 | 0.68 | ATM (0.55) | ATMSYKCTSBCTSLCTSS | |
| SCHEMBL8857090 | 0.68 | ATM (0.55) | ATMSYKCTSBCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617106-B1 | Methods for preparing oligonucleotides containing non-standard nucleotides | BENNER, STEVEN | 2003-09-09 | — | — | US | disclosed |
| US-6140496-A | Precursors for deoxyribonucleotides containing non-standard nucleosides | BENNER, STEVEN | 2000-10-31 | — | — | US | disclosed |