Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KYNU | Q16719 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1199787 | 0.91 | ITGB3 (0.53) | CTSLCTSSCTSBATMCTSK | |
| SCHEMBL1199790 | 0.91 | ITGB3 (0.53) | CTSLCTSSCTSBATMCTSK | |
| SCHEMBL7513292 | 0.91 | ITGB3 (0.53) | CTSLCTSSCTSBATMCTSK | |
| SCHEMBL1199066 | 0.89 | KYNU (0.54) | CTSLCTSSCTSBATMCTSK | |
| SCHEMBL15936883 | 0.89 | KYNU (0.54) | CTSLCTSSCTSBATMCTSK | |
| SCHEMBL1199068 | 0.89 | KYNU (0.54) | CTSLCTSSCTSBATMCTSK | |
| SCHEMBL17357790 | 0.89 | CTSS (0.50) | CTSLCTSSCTSBATMCTSK | |
| SCHEMBL13057155 | 0.86 | CTSK (0.49) | CTSLCTSSCTSBATMCTSK | |
| SCHEMBL2863999 | 0.86 | CTSS (0.50) | CTSLCTSSCTSBATMCTSK | |
| SCHEMBL7511181 | 0.84 | CTSS (0.53) | CTSLCTSSCTSBATMCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054919-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (CN) | 2024-03-14 | — | — | WO | disclosed |