Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212601 | 0.82 | ALDH1A1 (0.51) | HTTALDH1A1CYP2C19SETD7HTR2B | |
| SCHEMBL8218752 | 0.77 | SETD7 (0.59) | HTTALDH1A1CYP2C19SETD7HTR2B | |
| SCHEMBL10722320 | 0.76 | HTT (0.89) | HTTALDH1A1CYP2C19HTR2BTSHR | |
| SCHEMBL31350761 | 0.76 | FAAH (0.52) | HTTALDH1A1CYP2C19SETD7HTR2B | |
| SCHEMBL1929985 | 0.75 | HTT (0.70) | HTTALDH1A1CYP2C19HTR2BMAPT | |
| SCHEMBL7213758 | 0.74 | TSHR (0.54) | HTTALDH1A1CYP2C19SETD7HTR2B | |
| SCHEMBL12854656 | 0.74 | FAAH (0.55) | HTTALDH1A1CYP2C19SETD7HTR2B | |
| SCHEMBL3088384 | 0.74 | HTT (0.77) | HTTALDH1A1CYP2C19HTR2BTSHR | |
| SCHEMBL7217691 | 0.73 | ALDH1A1 (0.60) | HTTALDH1A1CYP2C19SETD7HTR2B | |
| SCHEMBL9036801 | 0.73 | MAPK1 (0.54) | HTTALDH1A1CYP2C19SETD7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38257-E1 | Piperdine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 2003-09-23 | — | — | US | disclosed |
| US-5393890-A | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1995-02-28 | — | — | US | disclosed |
| US-5250681-A | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1993-10-05 | — | — | US | disclosed |